SITC 2017 Abstract Titles – Microbiome

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Microbiome analyses in patients with previously treated, deficient DNA mismatch repair/microsatellite instability-high metastatic colorectal cancer treated with nivolumab ± ipilimumab: CheckMate 142

Scott Kopetz1, Vittorina Zagonel2, Michael J. Overman1, Ray McDermott3, Michael A. Morse4, Franklin L. Chen5, James Lee6, Rebecca A. Moss7, Lilan Ling8, Alexander Greenfield7, Danielle Greenawalt7, Z. Alexander Cao7

1MD Anderson Cancer Center, Houston, TX, USA 2Istituto Oncologico Veneto IOV-IRCSS, Padova, Italy 3St. Vincent's University, Dublin, Ireland 4Duke University Medical Center, Durham, NC, USA 5Novant Health Oncology Specialists, Winston-Salem, NC, USA 6University of Pittsburgh School of Medicine UPMC, Pittsburgh, PA, USA 7Bristol-Myers Squibb, Princeton, NJ, USA 8Memorial Sloan-Kettering Cancer Center, New York, NY, USA

Microbiome | Checkpoint blockade | Clinical study | Solid tumors


Association of Microbiome to Nivolumab Response in Metastatic Renal Cell Carcinoma (mRCC)

Manuel Maia1, Valeriy Poroyko1, Hae Won2, Paulo Bergerot1, Lorena Almeida1, Nazli Dizman1, JoAnn Hsu1, Jeremy Jones2, Ravi Salgia1, Sumanta Pal1

1City of Hope Comprehensive Cancer Center, Duarte, CA, USA 2Beckman Research Institute, City of Hope Comprehensive Cancer Center, Duarte, CA, USA

Checkpoint blockade | Microbiome


Commensal microbiota associated with anti-PD-1 efficacy in metastatic melanoma patients

Vyara Matson1, Jessica Fessler1, Riyue Bao1, Tara Chongsuwat1, Yuanyuan Zha1, Maria-Luisa Alegre1, Jason Luke1, Thomas Gajewski1

1University of Chicago, Chicago, IL, USA

Microbiome | Biomarkers | Clinical study | Solid tumors | Tumor infiltrating lymphocytes (TILs)