SITC 2017 Abstract Titles – irAE Management: Clinical Care and Best Practices

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Title

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P444

Inflammatory arthritis induced by the use of checkpoint inhibitors for immunotherapy of cancer

Noha Abdel-Wahab1,2, Jean H. Tayar1, Adi Diab1, Sang T. Kim1, Huifang Lu1, Maria E. Suarez-Almazor1

1The University of Texas MD Anderson Cancer Center, Houston, TX, USA 2Assiut University Hospitals, Faculty of Medicine, Assiut, Egypt

Autoimmunity | Checkpoint blockade | Immune toxicity | Inflammation

P445

Clinical features of immune checkpoint inhibitor-induced inflammatory arthritis differ in those treated with combination versus single agent therapy

Laura Cappelli1, Clifton Bingham1, Julie Brahmer1, Patrick Forde1, Dung Le1, Evan Lipson1, Jarushka Naidoo1, Lei Zhang1, Ami Shah1

1Johns Hopkins, Baltimore, MD, USA

Immune toxicity

P446

Immunosuppression Use and Clinical Outcomes in Patients with Immune Checkpoint Inhibitor -induced Inflammatory Arthritis

Laura Cappelli1, Clifton Bingham1, Julie Brahmer1, Patrick Forde1, Dung Le1, Evan Lipson1, Jarushka Naidoo1, Lei Zheng1, Ami Shah1

1Johns Hopkins, Baltimore, MD, USA

Immune toxicity

P447

Infliximab associated with faster symptom resolution compared to corticosteroids alone for management of immune related enterocolitis

Daniel H Johnson1, Chrystia Zobniw2, Van A Trinh2, Roland Bassett2, Junsheng Ma2, Jamie Anderson2, Jennifer Davis2, Jocelyn Joseph2, Marc Uemura2, Cassian Yee2, Rodabe Amaria2, Sapna Patel2, Hussein Tawbi2, Isabella Glitza2, Michael A Davies2, Michael Wong2, Scott Woodman2, Patrick Hwu2, Wen-Jen Hwu2, Yinghong Wang2, Adi Diab2

1University of Texas MD Anderson Cancer Center, Houston, TX, USA 2UT-MD Anderson Cancer Center, Houston, TX, USA

Checkpoint blockade | Immune toxicity

P448

Incidence of thyroid test function abnormalities in patients receiving immune-checkpoint inhibitors for cancer treatment

Nisha Patel1, Anais Oury1, Gregory Daniels1, Lyudmila Bazhenova1, Sandip Patel1

1University of California San Diego, La Jolla, CA, USA

Immune toxicity | Checkpoint blockade | Autoimmunity

P449

Neurotoxicity in patients with metastatic solid tumors treated with immune checkpoint inhibitors: a single institution retrospective analysis

Bianca Santomasso1, Rachna Malani1, Aya Haggiagi1, Jenessa Holder1, Yelena Shames1, Samuel Briggs1, Margaret Callahan1

1Memorial Sloan Kettering Cancer Center, New York, NY, USA

Checkpoint blockade

 

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