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Opportunities and challenges of active immunotherapy in dogs with B-cell lymphoma: a 5-year experience in two veterinary oncology centers

Published in the Journal for ImmunoTherapy of Cancer (JITC), is a research article concluding that the addition of immunotherapy to a traditional CHOP protocol is associated with improved outcome in dogs with B-cell lymphoma, regardless of histotype and evaluated prognostic factors. Moreover,...


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Anti-pancreatic tumor efficacy of a Listeria-based, Annexin A2-targeting immunotherapy in combination with anti-PD-1 antibodies

Published in the Journal for ImmunoTherapy of Cancer (JITC), is a research article in which a listeria vaccine-based immunotherapy was shown to be able to induce a tumor antigen-specific T cell response within the tumor microenvironment of a “cold” tumor such as PDAC and sensitize the tumor to...


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Carboplatin/paclitaxel, E7-vaccination and intravaginal CpG as tri-therapy towards efficient regression of genital HPV16 tumors

Published in the Journal for ImmunoTherapy of Cancer (JITC), is a short report suggesting that new vaccine formulations combined with local immunostimulation and standard-of-care chemotherapy have promise to further benefit patients with HPV-associated cancer. Authors: Sonia Domingos-Pereira ,...



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Vaccination with nanoparticles combined with micro-adjuvants protects against cancer

Published in the Journal for ImmunoTherapy of Cancer (JITC), is a research article demonstrating that it is possible to harness the physiological properties of the lymphatic system to optimize the induction of a protective T cell response. Authors: Mona O. Mohsen, Matthew D. Heath , Gustavo...


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Multiple antigen-engineered DC vaccines with or without IFNα to promote antitumor immunity in melanoma

Published in the Journal for ImmunoTherapy of Cancer (JITC), is a research article concluding that DC vaccines are a safe and reliable platform for promoting antitumor immunity. This combination with one month of high dose IFNα did not improve outcomes. Immune biomarker analysis in the blood...


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Split tolerance permits safe Ad5-GUCY2C-PADRE vaccine-induced T-cell responses in colon cancer patients

Published in the Journal for ImmunoTherapy of Cancer (JITC), is a research article in which the cancer vaccine Ad5-GUCY2C-PADRE was evaluated in a first-in-man phase I clinical study of patients with early-stage colorectal cancer to assess its safety and immunological efficacy. Authors: Adam E...


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The clinical application of cancer immunotherapy based on naturally circulating dendritic cells

Published in the Journal for ImmunoTherapy of Cancer (JITC), is a review article summarizing and discussing recent clinical developments and future prospects of natural dendritic cell based immunotherapy Authors: Kalijn F. Bol , Gerty Schreibelt , Katrin Rabold , Stefanie K. Wculek , ...


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Effective cancer immunotherapy by natural mouse conventional type-1 dendritic cells bearing dead tumor antigen

Published in the Journal for ImmunoTherapy of Cancer (JITC), is a research article providing preclinical proof-of-principle study is first to support the therapeutic efficacy of cancer immunotherapy with syngeneic dead tumor cell antigen-loaded mouse cDC1s, the equivalents of the human dendritic...


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Research Track - 2019 SITC Cancer Immunotherapy Winter School

2019 SITC Cancer Immunotherapy Winter School February 18-22, 2019 Delta Hotels Phoenix Mesa Mesa, Arizona Program Organizers Lisa H. Butterfield, PhD - PICI Research Center, Parker Institute for Cancer Immunotherapy; University of California, San Francisco Leisha A. Emens, MD, PhD - UPMC...

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