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Opportunities and challenges of active immunotherapy in dogs with B-cell lymphoma: a 5-year experience in two veterinary oncology centers

Published in the Journal for ImmunoTherapy of Cancer (JITC), is a research article concluding that the addition of immunotherapy to a traditional CHOP protocol is associated with improved outcome in dogs with B-cell lymphoma, regardless of histotype and evaluated prognostic factors. Moreover,...


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Improved efficacy against malignant brain tumors with EGFRwt/EGFRvIII targeting immunotoxin and checkpoint inhibitor combinations

Published in the Journal for ImmunoTherapy of Cancer (JITC), is a research article supporting the development of D2C7-IT and immune checkpoint blockade combinations for patients with malignant glioma. Authors: Vidyalakshmi Chandramohan, Xuhui Bao , Xin Yu , Scott Parker , Charlotte...


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Anti-pancreatic tumor efficacy of a Listeria-based, Annexin A2-targeting immunotherapy in combination with anti-PD-1 antibodies

Published in the Journal for ImmunoTherapy of Cancer (JITC), is a research article in which a listeria vaccine-based immunotherapy was shown to be able to induce a tumor antigen-specific T cell response within the tumor microenvironment of a “cold” tumor such as PDAC and sensitize the tumor to...


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Paired whole exome and transcriptome analyses for the Immunogenomic changes during concurrent chemoradiotherapy in esophageal squamous cell carcinoma

Published in the Journal for ImmunoTherapy of Cancer (JITC), is a research article seeking to analyze the early immunogenomic changes in ESCC induced by CCRT and to correlate them with clinical outcomes. The results provide a potential basis for combining immunotherapy with CCRT for the...



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Advances in Cancer Immunotherapy™ Webinar Series: Updates from the Field - Clinical Updates from SITC 2018 (Presentation Slides)

This webinar provided an update on developments in the field relating to content presented at the Advances in Cancer Immunotherapy programs and focused on applicable information for a clinical audience. More specifically, program organizers Christian M. Capitini, MD, and Zachary S. Morris,...

Advances in Cancer Immunotherapy Updates from the Field - Clinical Updates from SITC 2018.pdf




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Two cases of intrahepatic cholangiocellular carcinoma with high insertion-deletion ratios that achieved a complete response following chemotherapy combined with PD-1 blockade

Published in the Journal for ImmunoTherapy of Cancer (JITC), is a case report discussing two patients with relapsed ICC at stage IIIb were treated with PD-1 blockade combined with chemotherapy. These two cases suggest that indels might be a new predictor of PD-1 blockade response for ICC...


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Carboplatin/paclitaxel, E7-vaccination and intravaginal CpG as tri-therapy towards efficient regression of genital HPV16 tumors

Published in the Journal for ImmunoTherapy of Cancer (JITC), is a short report suggesting that new vaccine formulations combined with local immunostimulation and standard-of-care chemotherapy have promise to further benefit patients with HPV-associated cancer. Authors: Sonia Domingos-Pereira ,...