Annual Meeting & Pre-Conference Programs • Schedule

The following is the schedule for the 33rd Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC) taking place Nov. 7–11, 2018, in Washington, D.C.

Browse the full schedule by day by clicking the blue tabs below. This schedule will be updated as more information becomes known, so check back in the future for further updates! Also, visit the dedicate landing pages for the Pre-Conference Programs  and 33rd Annual Meeting page to learn more.

Click here to download the full schedule.

Wednesday, Nov. 7

Immune Escape: Current Understanding of Mechanisms and Advances in Therapeutics Approaches

Session I: Therapeutic Strategies to Overcome Immune Resistance

2 p.m.

Introduction
Daniel S. Chen – IMG Biosciences

2:05 p.m.

Biomarkers in Immune Escape
Priti S. Hegde, PhD – Genentech, Inc.

2:25 p.m.

Application Presentation 1

2:40 p.m.

Application Presentation 2

2:55 p.m.

Application Presentation 3

3:10 p.m.

Application Presentation 4

3:25 p.m.

Group Discussion

3:45 p.m.

Break

4 p.m.

Panel Discussion: Can CAR T cells Overcome and Influence Resistance to Other Treatment Modalities & New Concepts in Immune Checkpoint Blockade Designed to Overcome Local Immune Resistance
Co-Moderators:
Adrian Bot, MD, PhD – Kite a Gilead Company
Eric H. Rubin, MD – Merck
Panelists:
Daniel S. Chen, MD, PhD – IMG Biosciences
Gordon J. Freeman, PhD – Dana-Farber Cancer Center
Carl H. June, MD – University of Pennsylvania
Alan Korman, PhD – Bristol-Myers Squibb
Marcela Maus, MD, PhD – Massachusetts General Hospital

Session II: Underlying Mechanisms of Immune Escape

5 p.m.

Application Presentation 5

5:15 p.m.

Application Presentation 6

5:30 p.m.

Application Presentation 7

5:45 p.m.

Application Presentation 8

6 p.m.

Group Discussion

6:20 p.m.

Break

6:35 p.m.

Panel Discussion: Immune Resistance and the Tumor Micronenvironment & Using Oncolytic Immunotherapy to Overcome Immune Resistance in the Tumor Microenvironment
Co-Moderators:
Alessandra Cesano, MD, PhD – NanoString Inc.
Howard L. Kaufman, MD, FACS – Replimune Inc.
Panelists: Robert Coffin, PhD – Replimune Inc.
George Coukos, MD, PhD – University of Lausanne
Francesco M. Marincola, MD – Refuge Biotechnologies
Ira Mellman, PhD – Genentech/Roche
Darren Shafren, PhD – Viralytics Limited
Ryan Sullivan, MD – Massachusetts General Hospital
Dmitriy Zamarin, MD, PhD – Memorial Sloan Kettering Cancer Center

7:35 p.m.

Underlying Mechanisms of Immune Escape
Thomas F. Gajewski, MD, PhD – University of Chicago

Closing

7:55 p.m.

Salil Patel, PhD – Bristol-Myers Squibb

Immune Escape Reception

8 p.m.

Reception

Thursday, Nov. 8

Workshop on Nutrition, Metabolism and the Microbiome in Cancer Therapy

Introduction

8 a.m.

Program Organizer

Session I: The Impact of the Microbiome on Cancer Therapy

8:05 a.m. The Evolving Role of the Microbiome on Response to Cancer Therapy
Laurence Zitvogel, MD, PhD – Institute Gustave Roussy

8:30 a.m. Mechanistic Insights Into the Influence of Gut Microbiota on Anti-Tumor Immunity
Thomas F. Gajewski, MD, PhD – University of Chicago

9:00 a.m. The Microbiome as a Biomarker and a Therapeutic Target
Jennifer A. Wargo, MD, MMSc – University of Texas MD Anderson Cancer Center

9:30 a.m. Panel Discussion
Moderator: 
Laurence Zitvogel, MD, PhD – Institute Gustave Roussy
Panelists: Jennifer A. Wargo, MD, MMSc – University of Texas MD Anderson Cancer Center
Thomas F. Gajewski, MD, PhD – University of Chicago

9:45 a.m.

Break

Session II: Interplay of Nutrition, Metabolism, and the Microbiome

10:00 a.m. Microbial Metabolites and Their Impact on Immunity
Guido Kroemer, MD, PhD – Institute Gustave Roussy

10:30 a.m. Impact of Nutrition on Microbial Diversity and Composition
Carrie Daniel-MacDougall, MPH, PhD – University of Texas MD Anderson Cancer Center

11:00 a.m. The Influence of Nutrition on the Microbiome and Immune Function
Graham Britton, PhD – Icahn School of Medicine at Mount Sinai

11:30 a.m. The Gut Microbiota in Systemic Inflammation and Disease
Christian Jobin, PhD – University of Florida

Panel Discussion

Noon Moderator: Laurence Zitvogel, MD, PhD – Institute Gustave Roussy
Panelists:
Thomas F. Gajewski, MD, PhD – University of Chicago
Jennifer Wargo, MD, MMSc – University of Texas MD Anderson Cancer Center
Guido Kroemer, MD, PhD – Institute Gustave Roussy
Carrie Daniel-MacDougall, PhD – University of Texas MD Anderson Cancer Center
Christian Jobin, PhD – University of Florida
Graham Britton, PhD – Icahn School of Medicine at Mount Sinai

Primer on Tumor Immunology and Cancer Immunotherapy™

Introduction

8 a.m.

Jonathan Powell, MD, PhD – Johns Hopkins University School of Medicine

Session I: Generating Anti-Tumor Immunity

8:05 a.m. Adaptive Immunity to Tumors: Laying the Foundation for Immunotherapy
Timothy NJ Bullock, PhD – University of Virginia

8:35 a.m. Dendritic Cells
Tyler Curiel, MD – UT Health San Antonio

9:05 a.m. Innate Immunity
Amir Horowitz, PhD – Icahn School of Medicine at Mount Sinai

9:35 a.m. Panel Discussion

9:55 a.m.

Break

Session II: Breaking Through the Barriers - Passive Immunotherapy

10:10 a.m. Introduction
Timothy NJ Bullock, PhD – University of Virginia

10:15 a.m. Cancer Vaccines
Cornelis J.M. Melief, MD, PhD – ISA Pharmaceuticals BV and LUMC

10:45 a.m. Monoclonal Antibodies and Their Derivatives
Charles G. Drake, MD, PhD – Columbia University

11:15 a.m. Cytokines
Kim A. Margolin, MD – City of Hope

11:45 a.m. Panel Discussion

12:05 p.m.

Lunch

Session III: Analysis of Resistance and Response

1:05 p.m. Introduction
Jonathan Powell, MD, PhD – Johns Hopkins University School of Medicine

1:10 p.m. Mechanisms of Resistance: Extrinsic
Michael A. Curran, PhD – University of Texas MD Anderson Cancer Center

1:40 p.m. Mechanisms of Resistance: Checkpoint Receptors
Julie R. Brahmer, MD – Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

2:10 p.m. Biomarkers of Response & Immune Monitoring
Sacha Gnjatic, PhD – Icahn School of Medicine at Mount Sinai

2:40 p.m. Panel Discussion

3:10 p.m.

Break

Session IV: Current IO Immunotherapy

3:25 p.m. Introduction
Jonathan Powell, MD, PhD – Johns Hopkins University School of Medicine

3:30 p.m. Adoptive Cell Therapy
Patrick Hwu, MD – University of Texas MD Anderson Cancer Center

4 p.m. Combination Therapies
Leisha Emens, MD, PhD – University of Pittsburgh

4:30 p.m. Panel Discussion

4:50 p.m. Closing
Jonathan Powell, MD, PhD – Johns Hopkins University School of Medicine

Grant Writing: From Start to Finish, and Then Starting Again

Introduction

6:30 p.m. Jennifer Guerriero, PhD – Dana-Farber Cancer Institute

Session Schedule

6:35 p.m. Obtaining Funding in Academia - Identifying and Selecting the Appropriate Grant 
Pawel Kalinski, MD, PhD – Roswell Park

6:55 p.m. Obtaining Funding in Academia - Mechanics of Grant Writing
Thomas Gajewski, MD, PhD – University of Chicago

7:15 p.m. NIH/NCI Grants: The NIH Grant Review Process
Denise  R. Shaw, PhD – National Institutes of Health

7:35 p.m. MRA/Foundation Funding
Kristen Mueller, PhD – Melanoma Research Alliance

7:55 p.m. Panel Discussion
Moderator:
Lorenzo Falchi, MD – Columbia University Medical Center

8:25 p.m. Closing
Ana Carrizosa Anderson, PhD – Harvard Medical School

Friday, Nov. 9

Annual Meeting

7:15 a.m.

Presidential Champagne Toast & Membership Business Meeting

Presidential Welcome

8 a.m.

Lisa Butterfield, PhD – University of Pittsburgh

FDA & SU2C Update Session

8:05 a.m.

Food & Drug Administration Update
Raj Puri, MD, PhD – Food & Drug Administration

8:20 a.m.

Stand Up To Cancer Update

Keynote Address

8:35 a.m.

Introduction
Lisa H. Butterfield – University of Pittsburgh

8:40 a.m.

NextGen Cell-based Immunotherapies
Nicholas Restifo, MD – National Cancer Institute

Understanding the Tumor Microenvironment

Co-Chairs:

Bernard A. Fox, PhD – Earle A. Chiles Research Institute, Robert W. Franz Cancer Center
Stefani Spranger, PhD – Koch Institute for Integrative Cancer Research at MIT

9:25 a.m.

Introduction

9:30 a.m.

Genomic Approaches
Alexandra Snyder Charen, MD Merck

9:50 a.m.

Understanding the Tumor Immune Composition Using Quantitative and Spatially Resolved Imaging Mass Cytometry
Kurt A. Schalper, MD, PhD Yale School of Medicine

10:10 a.m.

Break

10:25 a.m.

Single Cell Sequencing
Alexandra-Chloe Villani, PhD Harvard Medical School

10:45 a.m.

Mouse Models of the TME
Tyler Jacks, PhD – Koch Institute for Integrative Cancer Research at MIT

11:05 a.m.

Abstract Presentation

11:20 a.m.

Abstract Presentation

11:35 a.m.

Panel Discussion

11:55 a.m.

Closing

Late-Breaking Abstract Session

Noon

Late-Breaking Abstract Session

Sparkathon: TimIOs

12:30 p.m.

Sparkathon: TimIOs Update
Yana Najjar, MD – University of Pittsburgh
Randy Sweis, MD – University of Chicago

12:45 p.m.

Lunch; Poster Viewing & Exhibits

Immune Checkpoints – Beyond PD-1

Co-Chairs:

Ana Carrizosa Anderson, PhD – Harvard Medical School
Charles G. Drake, MD, PhD – Columbia University Medical Center

2:15 p.m.

Introduction

2:20 p.m.

Lag-3
Dario A.A. Vignali University of Pittsburgh

2:45 p.m.

Clinical Development of anti-Tim-3
Catherine Sabatos-Peyton, PhD Novartis

3:10 p.m.

Break

3:25 p.m.

TIGIT
Hassane M. Zarour, MD UPMC Hillman Cancer Center

3:50 p.m.

4-1BB and Metabolism
Ignacio Melero, MD, PhD Clinica Universidad de Navarra-FIMA

4:15 p.m.

Abstract Presentation

4:30 p.m.

Abstract Presentation

4:45 p.m.

Closing

Early Phase 1 Clinical Trials

Co-Chairs:

David S. Hong, MD – University of Texas MD Anderson Cancer Center
Patricia LoRusso, DO – Yale University

2:15 p.m.

Introduction

2:20 p.m.

Abstract Presentation

2:35 p.m.

Abstract Presentation

2:50 p.m.

Expert Discussant

3:00 p.m.

Abstract Presentation

3:15 p.m.

Abstract Presentation

3:30 p.m.

Expert Discussant

4:50 p.m.

Break

Cytokines Reinvented

Co-Chairs:

James L. Gulley, MD, PhD, FACP – National Cancer Institute
Darrell J. Irvine, PhD – Massachusetts Institute of Technology

5:05 p.m.

Introduction
James L. Gulley, MD, PhD, FACP – National Cancer Institute

5:07 p.m.

NHS/IL15
Marijo Bilusic, MD, PhD National Cancer Institute, National Institutes of Health

5:27 p.m.

Pegylated Cytokines
Deborah Charych, PhD Nektar Therapeutics

5:47 p.m.

Combinations
K. Dane Wittrup, PhD Massachusetts Institute of Technology

6:07 p.m.

Abstract Presentation

6:17 p.m.

Abstract Presentation

6:27 p.m.

Closing
Darrell J. Irvine, PhD – Massachusetts Institute of Technology

Metabolic Manipulation of the TME

Co-Chairs:

Greg M. Delgoffe, PhD – University of Pittsburgh
Michele W. Teng, PhD – QIMR Berghofer Medical Research Institute

5:05 p.m.

Immune
Michele W. Teng, PhD – QIMR Berghofer Medical Research Institute

5:25 p.m.

Environment (Non-Immune)
Greg M. Delgoffe, PhD – University of Pittsburgh

5:45 p.m.

Abstract Presentation

6:00 p.m.

Abstract Presentation

6:15 p.m.

Abstract Presentation

6:30 p.m.

Poster Reception

Saturday, Nov. 10

Annual Meeting

7:20 a.m.

Annual Meeting Organizer Welcome

Policy Committee Update Session

7:25 a.m.

Policy Committee Update
Samir N. Khleif, MD Georgetown University

Richard V. Smalley, MD Memorial Lectureship

7:40 a.m.

Introduction
Lisa H. Butterfield, PhD – University of Pittsburgh

7:45 a.m.

Philip D. Greenberg, MD – Fred Hutchinson Cancer Research Center

Cell-Based Therapies for Solid Tumors

Co-Chairs:

Chantale Bernatchez, PhD – University of Texas MD Anderson Cancer Center 
Mitchell Cairo, MD – New York Medical College at Maria Fareri Children's Hospital   
Crystal L. Mackall, MD – Stanford University

8:30 a.m.

Introduction

8:35 a.m.

Pre-Clinical Approaches to CAR NK cell Therapy in Neuroblastoma and Sarcomas
Mitchell Cairo, MD – New York Medical College at Maria Fareri Children's Hospital   

8:55 a.m.

CAR T cell Therapies in Glioblastoma: A First Look
Christine Brown, PhD – City of Hope National Medical Center

9:15 a.m.

Break

9:30 a.m.

CAR T Cell Therapies in Solid Tumors
Gianpietro Dotti, MD – Baylor College of Medicine

9:50 a.m.

TIL Therapy for Melanoma and Beyond - Lessons Learned on Optimal Tumor Rejection Antigens for Solid Tumors
Steven A. Rosenberg, MD, PhD – National Cancer Institute, National Institutes of Health

10:10 a.m.

Abstract Presentation

10:25 a.m.

Abstract Presentation

10:40 a.m.

Panel Discussion

11:00 a.m.

Closing


Organized in collaboration with the International Society for Cellular Therapy (ISCT).

National Cancer Institute Update Session

11:05 a.m.

National Cancer Institute Update
Norman E. Sharpless, MD – National Cancer Institute

Late-Breaking Abstract Session

11:35 a.m.

Late-Breaking Abstract Session

Sparkathon: METIOR Incubator

12:05 p.m.

Sparkathon: METIOR Incubator
Alexandra Cadena, BS/BA – MD Anderson Cancer Center
Sebastiano Battaglia, PhD – Roswell Park Cancer Institute

Clinical Management of Cell Therapy Administration

Co-Chairs:

Harriet Kluger, MD – Yale University
Krista M. Rubin, MS, FNP-BC – Massachusetts General Hospital  

11:05 a.m.

Introduction

11:10 a.m. Tumor Infiltrating Lymphocytes
Ronnie Shapira, MD – Sheba Medical Center Hospital
11:30 a.m. Toxicities, Cytokine Storm, Neurotoxicity, Cardio Toxicity
Eric L. Smith, MD, PhD – Memorial Sloan Kettering Cancer Center
11:50 a.m. CAR T Cell Therapy and Cell Therapy in Pediatric Cancer Treatment
Shannon L. Maude, MD, PhD – Children's Hospital of Philadelphia Center for Childhood Cancer Research
12:10 p.m. Abstract Presentation
12:25 p.m. Closing

12:20 p.m.

Lunch; Poster Viewing & Exhibiting

Presidential Session

1:55 p.m.

Introduction
Lisa H. Butterfield, PhD – University of Pittsburgh

3:20 p.m.

Break

Advances in Immunotherapy of Breast and Gynecologic Cancers

Co-Chairs:

George Plitas, MD – Memorial Sloan Kettering Cancer Center
Alessandro Santin, MD – Yale School of Medicine

3:35 p.m.

Introduction

3:40 p.m. Ovary/Uterine/Cervix Cancers
Dmitrity Zamarin, MD, PhD – Memorial Sloan Kettering Cancer Center
4:05 p.m. Breast Cancer
Sylvia Adams, MD – New York University Cancer Institute
4:30 p.m. Abstract Presentation
4:45 p.m. Abstract Presentation

Advances in Immunotherapy of GI and Pancreatic Cancer

Co-Chairs:

Dung T. Le, MD – The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University
Herbert J. Zeh, MD – University of Pittsburgh Medical Center

3:35 p.m.

Introduction

3:40 p.m. Augmenting T cell Immunity in Pancreatic Cancer
Stephanie K. Dougan, PhD – Dana-Farber Cancer Institute
3:55 p.m. Marcophage Targeting in the Tumor Microenvironment
David G. DeNardo, PhD – Washington University
4:10 p.m. Stromal Targeting in Pancreatic Cancer
Sunil R. Hingorani, MD, PhD – Fred Hutchinson Cancer Research Center
4:25 p.m. Immunotherapy in Hepatocellular Carincoma (HCC)
Kevin Staveley-O'Carroll, MD – University of Missouri
4:40 p.m. Abstract Presentation
4:55 p.m. Closing

Advances in Immunotherapy of GU Tumors

Co-Chairs:

Arjun V. Balar, MD – Perlmutter Cancer Center - New York University Langone Medical Center
Padmanee Sharma, MD, PhD – University of Texas MD Anderson Cancer Center 

3:35 p.m. Introduction
3:40 p.m. Bladder Cancer
Arjun V. Balar, MD – Perlmutter Cancer Center - New York University Langone Medical Center
4:00 p.m. Renal Cell Carcinoma (RCC)
Eliezer Van Allen, MD – Dana-Farber Cancer Institute

4:20 p.m.

Prostate Cancer
Padmanee Sharma, MD, PhD – University of Texas MD Anderson Cancer Center

4:40 p.m. Abstract Presentation
4:55 p.m. Closing

Advances in Immunotherapy of Hematologic Malignancies

Co-Chairs:

Joshua Brody, MD – Mount Sinai School of Medicine
Elizabeth Shpall, MD – University of Texas MD Anderson Cancer Center

3:35 p.m.

CAR NK
Katayoun Rezvani, MD, PhD – University of Texas MD Anderson Cancer Center

4:00 p.m. CAR T cells
Stanley R. Riddell, MD – Fred Hutchinson Cancer Research Center
4:25 p.m. Checkpoint Blockade
Thomas Marron, PhD – Mount Sinai Hospital
4:45 p.m. Abstract Presentation

Organized in collaboration with the American Society of Blood and Marrow Transplant (ASBMT).

Advances in Immunotherapy of Lung, Head and Neck Cancer

Co-Chairs:

Naiyer A. Rizvi, MD – Columbia University Medical Center
Tanguy Seiwert, MD – University of Chicago

3:35 – 3:40 p.m.

Introduction

3:40 – 4:05 p.m. Lung Cancer (Tumor Genetics)
Nadeem Riaz, MD, MSc – Memorial Sloan Kettering Cancer Center

4:05  4:30 p.m. Head and Neck Cancer
Tanguy Seiwert, MD – University of Chicago

4:30 - 4:45 p.m. Abstract Presentation
4:45 – 5 p.m. Abstract Presentation

Advances in Immunotherapy of Pediatric Malignancies

Co-Chairs:

Kavita M. Dhodapkar, MD – Emory University
Crystal L. Mackall, MD – Stanford University

3:35 p.m.

Introduction

3:40 p.m.

Next Generation CAR T cells for Leukemia
Terry J. Fry, MD – Children's Hospital of Colorado

4:00 p.m. Vaccines
Duane A. Mitchell, MD, PhD – University of Florida
4:20 p.m. Tumor Microenvironment
Kavita M. Dhodapkar, MD – Emory University
4:40 p.m. Abstract Presentation
4:55 p.m. Closing

5 p.m.

Break

Basic Biology of Tregs

Co-Chairs:

Sergio A. Quezada, PhD – University College London
Dario A.A. Vignali, PhD – University of Pittsburgh

5:10 p.m.

CD-25
Sergio A. Quezada, PhD – University College London

5:31 p.m.

Basic Biology of Tregs and Targeting Tregs in  Cancer
Denise L. Faustman, MD, PhD – Harvard Medical School

5:51 p.m.

Abstract Presentation

6:01 p.m.

Abstract Presentation

6:11 p.m.

Abstract Presentation

6:21 p.m.

Question & Answer

Myeloid Derived Suppressive Populations

Co-Chairs:

Dmitry I. Gabrilovich, MD, PhD – The Wistar Institute
Sourav Ghosh, PhD – Yale School of Medicine

5:10 p.m.

Basic Macrophages & Mouse Models
Sourav Ghosh, PhD – Yale School of Medicine

5:35 p.m.

Translational & Clinical
Dmitry I. Gabrilovich, MD, PhD – The Wistar Institute

6:00 p.m.

Abstract Presentation 

6:15 p.m.

Abstract Presentation

Role of B cells in Immunotherapy & Toxicity

Co-Chairs:

Tullia C. Bruno, PhD – University of Pittsburgh
Madhav Dhodapkar, MD – Emory University

5:10 p.m.

Introduction
Madhav Dhodapkar, MD – Emory University

5:15 p.m.

Role of B cells in Tumors
Tullia C. Bruno, PhD – University of Pittsburgh

5:35 p.m.

Role of B cells in Autoimmunity
Kavita M. Dhodapkar, MD – Emory University

5:55 p.m.

Abstract Presentation

6:10 p.m.

Abstract Presentation

6:25 p.m.

Closing

Award Ceremony

6:35 p.m.

Award Ceremony

Poster Reception

7 p.m.

Poster Reception

Sunday, Nov. 11

Annual Meeting

7:30 a.m.

Annual Meeting Organizer Welcome

7:35 a.m.

Cancer Immunotherapy Trials Network Update 

Next Generation Bispecifics and Antibody-Like Molecules

8:05 – 10:15 a.m.

Co-Chairs:

Ignacio Melero, MD, PhD – FIMA - University of Navarra
Farhad Ravandi, MD – University of Texas MD Anderson Cancer Center

10:15 a.m.

Break

Immunoscore Update Session

10:30 a.m.

Immunoscore Update 
Jerome Galon, PhD – French National Institute of Health and Medical Research, Cordeliers Research Center

Hot Topic Symposium: Lessons from Recent Immuno-Oncology Trials - When Activity Estimation Diverges

10:45 a.m.

Introduction
Marc Theoret, MD – U.S. Food & Drug Administration

10:50 a.m.

Strength of Rationale, Potential Pharmacodynamic/Pharmacokinetic Considerations

11:05 a.m.

Biomarker Selection Considerations
Roy S. Herbst, MD, PhD – Yale Cancer Center

11:20 a.m.

Dosing and Dosage Regimen

11:35 a.m.

Clinical Development Strategy/Trial Design
Mario Sznol, MD – Yale Cancer Center

11:50 a.m.

Panel Discussion
Moderator: 
Marc Theoret, MD – U.S. Food & Drug Administration
Panelists:
Rajeshwari Sridhara, PhD – U.S. Food & Drug Administration
Roy S. Herbst, MD, PhD – Yale Cancer Center
Mario Sznol, MD – Yale Cancer Center

Adjourn

12:15 p.m.

Thank you for attending SITC 2018!

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