SITC Archive Library

Immunotherapy Biomarkers: Overcoming the Barriers Symposium - Mutational Landscapes and Immunotherapy Efficacy
April 2016
Bethesda, MD

Summary
In this slide presentation from "Immunotherapy Biomarkers: Overcoming the Barriers" Symposium in Bethesda MD in April 2016, Dr. Jianda Yuan, MD PhD (Merck Inc) describes how next-generation sequencing technologies, such as whole exome sequencing, are paving the way for precision oncology. Sequencing the whole exome has allowed for a comprehensive description of the mutational load (mutational landscape), which is valuable resource for immunotherapy, as neoantigen immunogenicity has been shown to correlate with response to treatment.

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