SITC's Cancer Immunotherapy Guidelines program is a collection of Clinical Practice Guidelines (CPGs) developed by multi-disciplinary panels of experts who draw from their own practical experience as well as evidence in the published literature and clinical trial data to develop evidence- and consensus-based recommendations. SITC uses as a model the Institute of Medicine's 2011 "Standards for Developing Trustworthy Clinical Practice Guidelines" to ensure the recommendations are unbiased, transparent and balanced will aid oncologists in effective clinical decision-making concerning patient selection, toxicity management, response evaluation, and the sequencing or combination of therapies, among other topics.
The Hepatocellular Carcinoma Immunotherapy Guideline Expert Panel was formed to generate consensus recommendations pertaining to the treatment of patients with hepatocellular carcinoma (HCC). Recently, the checkpoint inhibitor atezolizumab was approved by the U.S. FDA in combination with the anti-VEGF therapy bevacizumab as a first-line treatment for HCC. Additional immunotherapies targeting the PD-(L)-1 axis are approved second-line options. Ongoing trials are evaluating additional immunotherapeutic strategies for this disease state. Reflecting the evolving therapeutic landscape, SITC is currently developing an HCC CPG with topics including selection of appropriate immunotherapeutic regimens, recognition and management of adverse events, and patient quality of life considerations.
Published September 12, 2021 in the Journal for ImmunoTherapy of Cancer (JITC) as "Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of hepatocellular carcinoma"
SITC is pleased to offer free webinars featuring Expert Panel members from SITC's Hepatocellular Carcinoma Immunotherapy Guideline. These educational offerings are designed for healthcare providers who treat cancer patients including oncologists, physicians, disease specialists, registered nurses, nurse practitioners, pharmacists and physician assistants. The live webinars include a dedicated question-and-answer session providing the opportunity for attendees to converse with the faculty and ask questions about the guideline recommendations.
In this introductory webinar, Expert Panel members provide attendees with an overview of the published guideline and highlight selected recommendations that are applicable to some of the most common scenarios clinicians may encounter while treating their patients with immunotherapy. After attending this webinar, learners will be better able to implement immunotherapy treatments effectively and in accordance with the recommendations in the SITC CPG.
This advanced webinar is designed so that attendees will know how to appraise and classify organ-specific considerations for immunotherapy agents and toxicities, identify and manage clinically significant uncommon toxicities, and determine optimal sequencing of immunotherapies in relapsed and/or refractory disease.
Faculty engage attendees through a combination of case presentations with a “virtual tumor board” discussion and Q&A with diverse sub-specialty experts based on the needs of each particular case. This high-level webinar is designed so attendees will be able to execute the use of immunotherapy with increased confidence, plan management strategies for difficult cases, and identify and discuss areas of controversy in the immunotherapy field.
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