This workshop was developed in collaboration between ASTRO and Society for Immunotherapy of Cancer (SITC). The workshop will provide examples of different settings and study design to test currently available commercial immunotherapies combined with radiation therapy. The session will be limited to immunotherapies in clinical use and we will not discuss experimental drugs or mechanisms. We will first provide a brief introduction on the diversity of the mechanisms of resistance to current ICB. Three examples of original ongoing clinical trials will be presented, on the neoadjuvant, adjuvant and selected metastatic setting. This session will be especially useful for community and academic clinicians interested in designing novel clinical trials.
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