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iSBTc 25th Annual Meeting Biomarker Symposium 

02-27-2018 10:44

The International Society for Biological Therapy of Cancer (iSBTc) 25th Annual Meeting: Immuno-Oncology Biomarkers 2010 and Beyond: Perspectives from the iSBTc Biomarker Task Force
September 30, 2010
Building 10, Clinical Center
National Institutes of Health Campus
Bethesda, MD

Program Organizers
Lisa H. Butterfield, PhD - University of Pittsburgh
Mary L. (Nora) Disis, MD - University of Washington
Samir N. Khleif, MD - National Cancer Institute (CCR)
Francesco Marincola, MD - National Institutes of Health (CC, DTM)

Program Summary
This symposium aims achieve several goals. One is to define minimum quality standards and procedures for laboratories developing immunologic biomarkers for clinical trial analyses. The second is to discuss development of potency assays and the reporting of immunologic results. Third, review the current data supporting correlations of immunity and clinical outcome, and how knowledge from other fields (other then immunotherapy of cancer) can contribute to cancer immunotherapy. Lastly, determine which novel and high through-put technologies are now appropriate for use in cancer immunotherapy trials.

Target Audience
The target audience for these programs incorporates basic and clinical investigators from academic, regulatory and biopharmaceutical venues. The audience includes clinicians, researchers, students, post-doctoral fellows and allied health professionals.

Presentations and video recordings are available based on permission from presenters.


#Biomarkers #ClinicalTrials #BreastCancers #ColorectalCancer #ProstateCancer #Gynecologic Cancers #PresentationSlides #Biomarker Symposium #AnnualMeeting #TherapeuticAntibodies #Vaccines #AlliedHealth #Clinician #Industry #Oncologist #Researcher #2010 #RenalCellCarcinoma #Toxicities

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Defining the Critical Hurdles in Cancer Immunotherapy   355 KB   1 version
Uploaded - 02-27-2018
Meeting: iSBTc 25th Annual Meeting Biomarker Symposium; Presentation: Defining the Critical Hurdles in Cancer Immunotherapy; Presenter: Bernard A. Fox, PhD - Earle A. Chiles Research Institute; Date: Thursday, September 30, 2010
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NCI Workshop on Immunotherapy Biomarkers   41 KB   1 version
Uploaded - 02-27-2018
Meeting: iSBTc 25th Annual Meeting Biomarker Symposium; Session 1: Immunologic Monitoring: Standardization and Validation of Assays; Presentation: Recommendations for the iSBTc/FDA/NCI Workshop on Immunotherapy Biomarkers; Presenter: Lisa H. Butterfield, PhD - University of Pittsburgh; Date: Thursday, September 30, 2010
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CTL on ELISPOT Standardization, Story of Successful Stand...   138 KB   1 version
Uploaded - 02-27-2018
Meeting: iSBTc 25th Annual Meeting Biomarker Symposium; Session 1: Immunologic Monitoring: Standardization and Validation of Assays; Presentation: CTL on ELISPOT Standardization, Story of Successful Standardization; Presenter: Lisa H. Butterfield, PhD - University of Pittsburgh; Date: Thursday, September 30, 2010
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Harmonization of Immunologic Monitoring Across Institutions   1.52 MB   1 version
Uploaded - 02-27-2018
Meeting: iSBTc 25th Annual Meeting Biomarker Symposium; Session 1: Immunologic Monitoring: Standardization and Validation of Assays; Presentation: Harmonization of Immunologic Monitoring Across Institutions; Presenter: Cedrik M. Britten, MD - Association for Cancer Immunotherapy (CIMT); Date: Thursday, September 30, 2010
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Regulatory and Scientific Considerations for the Potency ...   73 KB   1 version
Uploaded - 02-27-2018
Meeting: iSBTc 25th Annual Meeting Biomarker Symposium; Session 2: Correlation of Immunity to Clinical Response and Potency Assays; Presentation: Regulatory and Scientific Considerations for the Potency Testing and Immune Monitoring; Presenter: Raj K. Puri, MD, PhD - U.S. Food and Drug Administration (CBER); Date: Thursday, September 30, 2010
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Immunologic Biomarkers as Correlates of Clinical Response...   460 KB   1 version
Uploaded - 02-27-2018
Meeting: iSBTc 25th Annual Meeting Biomarker Symposium; Session 2: Correlation of Immunity to Clinical Response and Potency Assays; Presentation: Immunologic Biomarkers as Correlates of Clinical Response after Cancer Immunotherapy; Presenter: Mary L. (Nora) Disis, MD - University of Washington; Date: Thursday, September 30, 2010
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Potency Analysis of Dendritic Cell Preparations Using Tra...   3.85 MB   1 version
Uploaded - 02-27-2018
Meeting: iSBTc 25th Annual Meeting Biomarker Symposium; Session 2: Correlation of Immunity to Clinical Response and Potency Assays; Presentation: Potency Analysis of Dendritic Cell Preparations Using Transcriptional Analysis; Presenter: David Stroncek, MD - National Institutes of Health; Date: Thursday, September 30, 2010
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Sipuleucel-T Product Potency Parameters and Correlation w...   711 KB   1 version
Uploaded - 02-27-2018
Meeting: iSBTc 25th Annual Meeting Biomarker Symposium; Session 2: Correlation of Immunity to Clinical Response and Potency Assays; Presentation: Sipuleucel-T Product Potency Parameters and Correlation with Overall Survival; Presenter: Mark W. Frohlih, MD - Dendreon Corporation; Date: Thursday, September 30, 2010
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Identification of Genetic Variants in IL28B (IFN-Iambda) ...   1.32 MB   1 version
Uploaded - 02-27-2018
Meeting: iSBTc 25th Annual Meeting Biomarker Symposium; Session 3: Novel Methodologies for Assessing the Immune Landscape: Clinical Utility of Novel Technologies; Presentation: Identification of Genetic Variants in IL28B (IFN-Iambda) as Major Predictors of Response to IFN-alfa Therapy for Chronic Hepatitis C; Presenter: Thomas R. O'Brian, MD - National Cancer Institute, Division of Cancer Epidemiology and Genetics; Date: Thursday, September 30, 2010
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Immune Profile Analysis of Tumor-Draining Lymph Nodes in ...   1.31 MB   1 version
Uploaded - 02-27-2018
Meeting: iSBTc 25th Annual Meeting Biomarker Symposium; Session 3: Novel Methodologies for Assessing the Immune Landscape: Clinical Utility of Novel Technologies; Presentation: Immune Profile Analysis of Tumor-Draining Lymph Nodes in Breast Cancer; Presenter: Peter P. Lee, MD - Stanford University; Date: Thursday, September 30, 2010
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Single Cell Network Profiling Technology and Applications...   2.74 MB   1 version
Uploaded - 02-27-2018
Meeting: iSBTc 25th Annual Meeting Biomarker Symposium; Session 4: Recommendations on Incorporation of Biomarkers into the Clinical Arena; Presentation: Single Cell Network Profiling Technology and Applications in Immunological Monitoring; Presenter: Peter P. Lee, MD - Stanford University; Date: Thursday, September 30, 2010
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Biostatistical Considerations in Immunotherapy Biomarkers...   779 KB   1 version
Uploaded - 02-27-2018
Meeting: iSBTc 25th Annual Meeting Biomarker Symposium; Session 4: Recommendations on Incorporation of Biomarkers into the Clinical Arena; Presentation: Biostatistical Considerations in Immunotherapy Biomarkers in Clinical Trials; Presenter: Daniel Normolle, PhD - University of Pittsburgh Cancer Institute; Date: Thursday, September 30, 2010
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Prospects for New Clinical Flow Cytometry Assays   319 KB   1 version
Uploaded - 02-27-2018
Meeting: iSBTc 25th Annual Meeting Biomarker Symposium; Session 4: Recommendations on Incorporation of Biomarkers into the Clinical Arena; Presentation: Prospects for New Clinical Flow Cytometry Assays; Presenter: Holden T. Maecker, PhD - Stanford University Medical Center; Date: Thursday, September 30, 2010
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Are We Ready for Clinical Implementation?   427 KB   1 version
Uploaded - 02-27-2018
Meeting: iSBTc 25th Annual Meeting Biomarker Symposium; Session 4: Recommendations on Incorporation of Biomarkers into the Clinical Arena; Presentation: Predictive Biomarkers for Tumor Immunotherapy: Are We Ready for Clinical Implementation?; Presenter: Howard L. Kaufman, MD, FACS - Rush University Medical Center; Date: Thursday, September 30, 2010