SITC Archive Library

iSBTc 22nd Annual Meeting 

02-20-2018 12:05

The International Society for Biological Therapy of Cancer (iSBTc) 22nd Annual Meeting
November 2-4, 2007
Seaport World Trade Center in Boston, Massachusetts

Program Organizers
George Coukos, MD, PhD - University of Pennsylvania Medical Center
F. Stephen Hodi, MD - Dana-Farber Cancer Institute
James C. Yang, MD - National Cancer Institute

Program Summary
The Annual Meeting featured an interactive environment that facilitated productive discourse among clinicians, researchers, students, post-doctoral fellows, and allied health professionals from the US, Europe, Asia and beyond. The meeting included over 50 high-quality scientific lectures and 135 posters related to angiogenesis and vascular therapies, cellular therapies, characterizing the host response to cancer, combination therapy for cancer, cytokines, immunoregulation and mediated, tolerance, inflammation and innate immunity, new agents, tumor microenvironment, tumor recognition and immune evasion, and vaccines and dendritic cells.

Intended Audience
The target audience for these programs incorporates basic and clinical investigators from academic, regulatory and biopharmaceutical venues. The audience includes clinicians, researchers, students, post-doctoral fellows and allied health professionals.

Presentations and video recordings are available based on permission from presenters.


#ClinicalTrials #BrainCancers #BreastCancers #ColorectalCancer #GastrointestinalCancers #HeadandNeckCancers #Neuroblastoma #ProstateCancer #PresentationSlides #AnnualMeeting #AdoptiveCellTherapy #SITC #Toxicities #CombinationTherapy #Cytokines #TherapeuticAntibodies #Vaccines #Clinician #Industry #RegisteredNurse #Oncologist #Researcher #2007​​​​​​​​​​​ #ColonCancer #Lymphoma #Melanoma #Myeloma #RenalCellCarcinoma

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Interferons (IFNs) for Cancer Defining Biological Respons...   2.82 MB   1 version
Uploaded - 02-20-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: Interferons (IFNs) for Cancer Defining Biological Response Modification and Full Therapeutic Potential; Presenter: Ernest C. Borden, MD - Cleveland Clinic Foundation; Date: Friday, November 2, 2007
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Adoptive Cellular Therapy - Sustained Regression of Large...   1.73 MB   1 version
Uploaded - 02-20-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: Adoptive Cellular Therapy - Sustained Regression of Large Tumor Burdens with In Vitro Expanded T-Cells; Presenter: James C. Yang, MD - National Cancer Institute; Date: Friday, November 2, 2007
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Targeting Tumors with Genetically Enhanced T Lymphocytes   1.92 MB   1 version
Uploaded - 02-20-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation:Targeting Tumors with Genetically Enhanced T Lymphocytes; Presenter: Michael Sadelain, MD, PhD - Memorial Sloan-Kettering Cancer Center; Date: Friday, November 2, 2007
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Engineering Cytolytic Effector Cells for Glioma Immunothe...   1.26 MB   1 version
Uploaded - 02-20-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: Engineering Cytolytic Effector Cells for Glioma Immunotherapy Using Gene Insertion and Zinc Finger Nuclease Genomic Editing; Presenter: Michael C.V. Jensen, MD - City of Hope, Beckman Research Institute; Date: Friday, November 2, 2007
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T-Cell Therapy for the Control of EBC-Related Nasopharnyg...   242 KB   1 version
Uploaded - 02-20-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: T-Cell Therapy for the Control of EBC-Related Nasopharnygeal Carcinoma; Presenter: Paulo Pedrazzoli, MD - Ospedale Niguarda Ca' Granda ; Date: Friday, November 2, 2007
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Stat3 Mediates a Crosstalk between Tumor Cells and Immune...   1.31 MB   1 version
Uploaded - 02-20-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: Stat3 Mediates a Crosstalk between Tumor Cells and Immune Cells in the Tumor; Presenter: Hua Yu, PhD - City of Hope National Medical Center ; Date: Friday, November 2, 2007
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Antibody Immunity to a Panel of Oncogenic Proteins may Pr...   288 KB   1 version
Uploaded - 02-20-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: Antibody Immunity to a Panel of Oncogenic Proteins may Predict Presence of Colon Cancer and Stage of Disease; Presenter: Vivian Goodell, MPH - University of Washington; Date: Friday, November 2, 2007
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A Possible Role of Regulatory T-Cells Survival Difference...   203 KB   1 version
Uploaded - 02-20-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: A Possible Role of Regulatory T-Cells Survival Differences between Helicobacter Pylori Positive and Negative Gastric Cancer Patients after Curative Tumor Resection; Presenter: Hauke Winter, MD - Klinikum Grosshadem, Ludwig-Maximilians University of Munich ; Date: Friday, November 2, 2007
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A New Approach for Prognostication in Stage IV Melanoma   497 KB   1 version
Uploaded - 02-20-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: Immunophenotypic Analysis of Melanoma Metastases: A New Approach for Prognostication in Stage IV Melanoma; Presenter: Alicia M. Terando, MD - John Wayne Cancer Institute; Date: Friday, November 2, 2007
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Memory Cells via CD137   305 KB   1 version
Uploaded - 02-20-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: A Cell-Based Vaccine for Neuroblastoma Induces VLA-2 (CD49b) on CD8+ T Effector/Memory Cells via CD137; Presenter: Rimas J. Orentas, PhD - Medical College of Wisconsin; Date: Friday, November 2, 2007
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IL-24 and its Role in Wound Healing   483 KB   1 version
Uploaded - 02-20-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: IL-24 and its Role in Wound Healing; Presenter: Nancy J. Poindexter, PhD - MD Anderson Cancer Center; Date: Friday, November 2, 2007
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Memory Cell-Mediated INF-Gamma and FASL-Dependent Elimina...   189 KB   1 version
Uploaded - 02-20-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: Intra-Tumoral IL-12 Promotes CD8+ T-Effector/Memory Cell-Mediated INF-Gamma and FASL-Dependent Elimination of CD4+CD25+FOX3+ T-Suppressor Cells from Tumors; Presenter: Mehmet O. Kilinc, PhD - University at Buffalo/SUNY; Date: Friday, November 2, 2007
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Impaired Angiogenesis in Aminopeptidase N-Null Mice   299 KB   1 version
Uploaded - 02-20-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: Impaired Angiogenesis in Aminopeptidase N-Null Mice; Presenter: Roberto Rangel, PhD - MD Anderson Cancer Center Date: Friday, November 2, 2007
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Adoptive T Cell Therapy - Grand Challenges and Opportuni...   3.86 MB   1 version
Uploaded - 02-20-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: Keynote: Adoptive T Cell Therapy - Grand Challenges and Opportunities; Presenter: Carl H. June, PhD - University of Pennsylvania; Date: Saturday, November 3, 2007
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Different Flavors of Regulatory T-Cell (Treg) Subsets in ...   702 KB   1 version
Uploaded - 02-20-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: Different Flavors of Regulatory T-Cell (Treg) Subsets in Patients with Cancer and Their Role in Tumor Escape; Presenter: Christoph Bergmann, MD, PhD - University of Duisburg-Essen; Date: Saturday, November 3, 2007
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Fox3 is Expressed by Tumor Cells, Virally Transfomred B C...   851 KB   1 version
Uploaded - 02-20-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: Fox3 is Expressed by Tumor Cells, Virally Transfomred B Cells, and Germ Cells; Presenter: Weisan Chen, PhD - Ludwig Institute for Cancer Research; Date: Saturday, November 3, 2007
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Using Gene Transfer to Retarget Cytotoxic T Lymphocytes   1.21 MB   1 version
Uploaded - 02-20-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: Using Gene Transfer to Retarget Cytotoxic T Lymphocytes; Presenter: Malcolm K. Brenner, MD, PhD - Baylor College of Medicine; Date: Saturday, November 3, 2007
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Therapeutically Accessible Molecules that Regulate the Re...   912 KB   1 version
Uploaded - 02-20-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: Therapeutically Accessible Molecules that Regulate the Regulators; Presenter: Drew M. Pardoll, Md, PhD - Johns Hopkins University School of Medicine; Date: Saturday, November 3, 2007
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Tumor-Derived Marcrophage Mirgration Inhibitory Factor (M...   296 KB   1 version
Uploaded - 02-20-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: Tumor-Derived Marcrophage Mirgration Inhibitory Factor (MIF) Inhibits Immune Reactivity to Neuroblastoma In Vivo; Presenter: Bryon D. Johnson, PhD - Medical College of Wisconsin; Date: Saturday, November 3, 2007
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5-aza-2 Deoxycytidine Treatement Increases Expression of ...   166 KB   1 version
Uploaded - 02-20-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: 5-aza-2 Deoxycytidine Treatement Increases Expression of Tumor Associated Antigens in Human Melanoma; Presenter: Timothy Haggerty, PhD - CytoCure LLC; Date: Saturday, November 3, 2007
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A Phase II Study of Tremelimumab (CP-675,206), an Anti-CL...   192 KB   1 version
Uploaded - 02-20-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: A Phase II Study of Tremelimumab (CP-675,206), an Anti-CLTA4 Monoclonal Antibody, in Patients with Refractory Metastatic Colorectal Cancer; Presenter: Ki Y. Chung, MD - Memorial Sloan-Kettering Cancer Center; Date: Saturday, November 3, 2007
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EGFRVII Vaccine (CDX-110) Along and with Simultaneous Tem...   1.10 MB   1 version
Uploaded - 02-20-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: EGFRVII Vaccine (CDX-110) Along and with Simultaneous Temozolomide in Patients with Newly Diagnosed, Resected, EGFRVIII Positive GMB; Presenter: John Sampson, MD, PhD - Duke University Medical Center; Date: Saturday, November 3, 2007
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Challenges and Opportunities in Capitalizing on Active T...   574 KB   1 version
Uploaded - 02-20-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: Novel Agents in Renal Cell Carcinoma: Challenges and Opportunities in Capitalizing on Active Therapy; Presenter: Brain I. Rini, MD - Cleveland Clinic Taussig Cancer Center; Date: Saturday, November 3, 2007
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Retrospective Analysis of Interleukin-2 Therapy in Patien...   296 KB   1 version
Uploaded - 02-20-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: Retrospective Analysis of Interleukin-2 Therapy in Patients with Metastatic Renal Cell Carcinoma Who had Received Prior Antiangiogenic Therapy; Presenter: Talya Schwarzberg, MD - Beth Israel Deaconess Medical Center; Date: Saturday, November 3, 2007
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FasL-Mediated Pathways   498 KB   1 version
Uploaded - 02-20-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: CD4+CD25highFoxp3+ T Regulatory Cells Kill Autologous CD8(+) and CD4(+) T Cells Using GranzymB and Fas/FasL-Mediated Pathways; Presenter: Laura Strauss, PhD - San Raffaele Telethon Institute for Gene Therapy; Date: Saturday, November 3, 2007
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Update- 2006 Mini-Symposium   281 KB   1 version
Uploaded - 02-21-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: Update- 2006 Mini-Symposium ; Presenter: Michael B. Atkins, MD - Beth Israel Deaconess Medical Center; Date: Sunday, November 4, 2007
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Update - National Cancer Institute Immunotherapy Agent Wo...   181 KB   1 version
Uploaded - 02-21-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: Update - National Cancer Institute Immunotherapy Agent Workshop; Presenter: Martin A. Cheever, MD - Fred Hutchinson Cancer Research Center; Date: Sunday, November 4, 2007
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The Development of Provenge (Sipuleucel-T) an Active Cell...   889 KB   1 version
Uploaded - 02-21-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: The Development of Provenge (Sipuleucel-T) an Active Cellular Immunotherapy for Prostate Cancer; Presenter: David L. Urdal, PhD - Dendreon Corporation; Date: Sunday, November 4, 2007
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Long-Term Survival in Patients with Metastatic Melanoma V...   1.10 MB   1 version
Uploaded - 02-21-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: Long-Term Survival in Patients with Metastatic Melanoma Vaccinated with Melanoma Antigen Loaded Dendritic Cells; Presenter: Josher W. Fay, MD - Baylor University Medical Center; Date: Sunday, November 4, 2007
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Pre-Clinical and Clinical Studies and Implications for C...   849 KB   1 version
Uploaded - 02-21-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: IMA901, A Novel Multi-Peptide Vaccine for the Treatment of Renal Cell Carcinoma: Pre-Clinical and Clinical Studies and Implications for Combination with Other Agents; Presenter: Harpreet Singh, PhD - Immatics Biotechnologies CmbH; Date: Sunday, November 4, 2007
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Essential Tumor Antigens in Breast Cancer   281 KB   1 version
Uploaded - 02-21-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: Insulin like Growth Factor Receptor Family Members: Essential Tumor Antigens in Breast Cancer; Presenter: Mary L. Disis, MD - University of Washington; Date: Sunday, November 4, 2007
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Impact of Delayed Effect   114 KB   1 version
Uploaded - 02-21-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: Hot Topic: Vaccines/Dendritic Cells - Dendreon Effect Size Estimates: Impact of Delayed Effect; Presenter: Brent A. Blumenstein, PhD - TriArc Consulting; Date: Sunday, November 4, 2007
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Dendritic Cells - Basis for Drug Approval in US   55 KB   1 version
Uploaded - 02-21-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: Hot Topic: Vaccines/Dendritic Cells - Basis for Drug Approval in US; Presenter: Lee S. Simon, MD - Beth Israel Deaconess Medical Center; Date: Sunday, November 4, 2007
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Dendritic Cells - A Clinical Perspective   330 KB   1 version
Uploaded - 02-21-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: Hot Topic: Vaccines/Dendritic Cells - A Clinical Perspective ; Presenter: Charles Drake, MD, PhD - Johns Hopkins University; Date: Sunday, November 4, 2007
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Dendritic Cells - The Provenge (sipuleucel-T) Experience ...   81 KB   1 version
Uploaded - 02-21-2018
Meeting: iSBTc 22nd Annual Meeting; Presentation: Hot Topic: Vaccines/Dendritic Cells - The Provenge (sipuleucel-T) Experience - A Regulatory Perspective; Presenter: David L. Urdal, PhD - Dendreon Corporation; Date: Sunday, November 4, 2007