Workshop Overview Leadership Hotel and Travel Program Agenda
Program Purpose
The Immuno-Oncology Biomarkers Workshop will identify the next steps for action in immunotherapy biomarker development. It will provide a forum for energetic discussion about the collaborative efforts across several societies and consortia, make progress on identification and analysis of novel biomarkers, and tackle data analysis and specimen sharing. The final session will bring together representatives from the fields of immune-oncology research, infectious disease, autoimmune disease and cell biology to discuss opportunities for cross-disciplinary collaboration to advance biomarker development.
Panel discussions following each didactic presentation will allow all participants to contribute to the conversation, and to shape the innovative collaborations, next projects and other outputs that the SITC Immune Biomarkers Committee will incorporate over the next several years.
Intended Audience
The target audience for this program includes a broad representation from academia, biotech, pharma, government, researchers and early career individuals who wish to understand the biomarkers state of the art, discuss current hurdles to further success, and consider recommendations to move the field forward.
Educational Objectives
Upon completion of this meeting, participants will be able to:
- Discuss methods of validation of biomarkers to predict response to immunotherapy in cancer
- Describe effective approaches for data and specimen sharing related to biomarkers
- Describe how to collaborate across disciplines in order to advance biomarker research
- Describe existing processes and standards of practice regarding obtaining and processing biospecimens
Program Committee
Chair – Lisa H. Butterfield, PhD – University of Pittsburgh
Mary L. Disis, MD, FACP – University of Washington
Bernard A. Fox, PhD – Earle A. Chiles Research Institute, Robert W. Franz Cancer Center
David Kaufman, MD, PhD – Bill & Melinda Gates Medical Center
Samir N. Khlief, MD – Georgetown University
Ena Wang, MD – AbbVie Biotherapeutics Corp.
Immuno-Oncology Biomarkers: State of the Art is supported in part by
AstraZeneca Pharmaceuticals LP, Bristol-Myers Squibb, Genentech, Incyte Corporation, and Merck & Co., Inc.
Hotel and Travel
Hotel
InterContinental Mark Hopkins Hotel
999 California Street, San Francisco, California 94108
Contact: 415-392-3434 | Fax: 415-421-3302
SITC has organized a block of rooms at $269 per night at the meeting hotel. Click here to book your hotel room on the InterContinental Mark Hopkins Hotel website.
Click on the “BOOK NOW” link in the upper right hand corner of the page. Click "More Options" next to the gold Search button and the SITC discount Group Code “SIC” will automatically show and allow for the discounted group rates.
To make your hotel reservation by phone, please contact the IHG Reservation Department at +1 800-662-4455. Identify yourself as a participant of the SITC Group (Code: SIC) in order to receive the negotiated rates of $269 per night.
Hotel Reservation deadline is Wednesday, May 2, 2018. After that time, reservations are considered based on availability.
Travel
Major Airports
The San Francisco Bay Area has three major airports with airline service.
For travel tips and security updates, please visit tsa.gov.
Shuttles
Intercontinental Mark Hopkins Hotel does not offer shuttle service. The BayPorter Express and SuperShuttle provide shuttle services from both San Francisco International Airport and Oakland International Airport to downtown San Francisco.
Fares are approximate and subject to change.
Taxi Services
Taxi stands are located at all the major airports as well as most hotels, attractions and shopping centers. From the San Francisco International Airport to the InterContinental Mark Hopkins Hotel fares are approximately $45*. From the Oakland International Airport, the fare is $40* to the hotel. For more information about the taxi fares, please visit www.taxifarefinder.com.
*Fares are approximate and subject to change.
Trains
Trains arrive at the SFO International Terminal every 15 minutes and it's just 30 minutes to downtown San Francisco. A one-way ticket from SFO to downtown is approximately $9.65*. The BART (Bay Area Rapid Transit) station at SFO is located in the International Terminal. The Oakland Airport BART station is located just across from the Terminal 1 baggage claim area and a short walk from Terminal 2. *Fares are approximate and subject to change.
Registration
Online registration is closed.
Registration rates for members and non-members are listed below:
|
Member Type
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Early Registration Rate
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Onsite Registration Rate
|
|
Industry Member
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$880
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$930
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Industry Non-Member
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$1,100
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$1,150
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Non-Industry Member
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$400
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$450
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Non-Industry Non-Member
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$480
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$530
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Cancellation Policy
All cancellations must be received in writing. You may fax your cancellation to +1 888-289-9844 or e-mail education@sitcancer.org. Requests must be submitted by April 14, 2018. A $50 processing fee will be charged for all cancellations. All refunds will be processed after the programs; you will receive an e-mail confirmation. No refunds will be granted if cancellation is received after April 14, 2018. Special considerations will be given for health or family emergencies if requested in writing to education@sitcancer.org no later than 15 business days after the last day of the programs.
Program Agenda (
Tentative Schedules as of April 9, 2018)
Wednesday May 16, 2018
Registration
Time: 7:00 – 8:00 a.m.
Location: Lobby Terrace
Breakfast
Time: 7:00 – 8:00 a.m.
Location: Lobby Terrace
Welcome and Introduction
Time: 8:00 – 8:15 a.m.
Location: Peacock Court
Organizer: Lisa H. Butterfield, PhD – University of Pittsburgh
Session I: State of the Field
Time: 8:15 – 11:30 a.m.
Location: Peacock Court
Co-Chairs: Stacey Adam, PhD – Foundation for the National Institutes of Health
Helen Chen, MD – National Cancer Institute
8:15 a.m. Overview of Cancer Immune Monitoring and Analysis Centers (CIMACs)-CIDC Network
William D. Merritt, PhD – National Cancer Institute
8:35 a.m. CIMAC Institutions and Cancer Immunologic Data Commons (CIDC)
Sacha Gnjatic, PhD – Ichan School of Medicine at Mount Sinai
Kara Davis, DO – Stanford University
Ignacio Wistuba, MD – MD Anderson Cancer Center
James Lindsay, PhD – Dana-Farber Cancer Institute
8:55 a.m. Comprehensive Biomarkers on Immunotherapy Clinical Trials: A Longitudinal Approach
Ignacio Wistuba, MD – MD Anderson Cancer Center
9:00 a.m. The Partnership for Accelerating Cancer Therapies (PACT): A Public-Private Partnership to Aid Standardization of Immune Therapy Biomarkers
Stacey Adam, PhD – Foundation for the National Institutes of Health
9:20 a.m. Parker Institute for Cancer Immunotherapy's "TESLA" (Tumor NeoantigEN SeLection Alliance) Collaborative Project: Neoantigen Selection and the TESLA Consortium
Fred Ramsdell, PhD – Parker Institute for Cancer Immunotherapy
9:40 a.m. Break
Location: Lobby Terrace
9:55 a.m. The MANAFEST Assay for Monitoring Anti-Tumor Immunity
Kellie N. Smith, PhD – Johns Hopkins School of Medicine
10:15 a.m. Transcriptional Analysis of Peripheral Blood and Update on the ECOG1608 Trial
Davide Bedognetti, MD, PhD – Sidra Medical and Research Center
10:35 a.m. Panel Discussion
11:30 a.m. Lunch
Location: Lobby Terrace
Session II: Validation of Biomarkers Identification and Analysis
Time: 12:30 – 4:45 p.m.
Location: Peacock Court
Co-Chairs: Bernard A. Fox, PhD – Earle A. Chiles Research Institute, Robert W. Franz Cancer Center
Sacha Gnjatic, PhD – Icahn School of Medicine at Mount Sinai
12:30 p.m. Introduction
Bernard A. Fox, PhD – Earle A. Chiles Research Institute, Robert W. Franz Cancer Center
12:35 p.m. Immunoscore Task Force
Bernard A. Fox, PhD – Earle A. Chiles Research Institute, Robert W. Franz Cancer Center
12:55 p.m. Multi-Parametric Biomarkers I: Seeing is Believing - Dissecting Local Immune-Tumor Interactions with Advanced Imaging Techniques Chen Zhao, MD – National Institutes of Health
1:15 p.m. Multi-Parametric Biomarkers II: High-Dimensional Profiling of Cancer-Specific vs. Bystander Tumor Infiltrating T cells
Evan Newell, PhD – Singapore Immunology Network
1:35 p.m. Multispectral Imaging: Low Dimensionality Imaging Approach Kurt Schalper, MD, PhD – Yale School of Medicine
1:55 p.m. Multispectral Imaging: Higher Dimensionality Imaging Approach Michael Angelo, MD, PhD – Stanford University School of Medicine
2:15 p.m. Break
Location: Lobby Terrace
2:30 p.m. Machine Learning I David Furman, PhD – Stanford University School of Medicine
2:50 p.m. Machine Learning II: Predicting Tumor Evolution from Immune Interactions
Marta Luksza, PhD – Institute for Advanced Study
3:10 p.m. Panel Discussion
4:10 p.m. Closing Remarks
Bernard A. Fox, PhD – Earle A. Chiles Research Institute, Robert W. Franz Cancer Center
4:30 p.m. Reception
Thursday May 17, 2018
Registration
Time: 7:00 – 8:00 a.m.
Location: Lobby Terrace
Breakfast
Time: 7:00 – 8:00 a.m.
Location: Lobby Terrace
Session III: Data and Specimen Sharing
Time: 8:00 a.m. – 2:10 p.m.
Location: Peacock Terrace
Co-Chairs: Samir N. Khleif, MD – Georgetown University
Elad Sharon, MD, MPH – National Cancer Institue
8:00 a.m. Introduction
Samir N. Khleif, MD – Georgetown University
8:05 a.m. Cancer Immunologic Data Commons (CIDC)
James Lindsay, PhD – Dana-Farber Cancer Institute
8:25 a.m. Data Sharing for PACT and FNIH
Stacey Adam, PhD – Foundation for the National Institutes of Health
8:45 a.m. Parker Institute for Cancer Immunotherapy
Pier Federico Gherardini, PhD – Parker Institute for Cancer Immunotherapy
9:05 a.m. Stand Up To Cancer (SU2C) Constantine Mitsiades, MD, PhD – Dana-Farber Cancer Institute
9:25 a.m. Industry Perspective: Bristol-Myers Squibb
Shilpa Demes, PhD – Bristol-Myers Squibb
9:40 a.m. Industry Perspective: Genentech
Priti Hegde, PhD – Genentech
9:55 a.m. Academic Perspective
Samir N. Khleif, MD – Georgetown University
10:15 a.m. Break
Location: Lobby Terrace
10:30 a.m. Cancer Immunotherapy Trials Network (CITN): Data Management and Specimen Sharing
Martin A. Cheever, MD – Fred Hutchinson Cancer Research Center
Steven P. Fling, PhD – Fred Hutchinson Cancer Research Center
10:50 a.m. American Association for Cancer Research (AACR) Project GENIE (Genomics Evidence Neoplasia Information Exchange): Driving Discovery in Immuno-oncology Through Data Sharing
Shawn Sweeney, PhD – American Association for Cancer Research
11:10 a.m. Oncology Research Information Exchange Network (ORIEN)
Hongyue Dai, PhD – M2GEN
11:30 a.m. Lunch
Location: Lobby Terrace
12:30 p.m. Immune-Related Adverse Events John M. Kirkwood, MD – UPMC Hillman Cancer Center
12:50 p.m. Sparkathon Project TimIOs
Yana Najjar, MD – University of Pittsburgh
Randy Sweis, MD – University of Chicago
1:10 p.m. Panel Discussion
2:10 p.m. Break
Location: Lobby Terrace
Session IV: Collaboration Across Disciplines
Time: 2:25 – 5:00 p.m.
Location: Peacock Terrace
Co-Chairs: David Kaufman, MD, PhD – Bill & Melinda Gates Medical Research Institute
Francesco M. Marincola, MD
2:25 p.m. Introduction
David Kaufman, MD, PhD – Bill & Melinda Gates Medical Research Institute
2:30 p.m. Parker Institute for Cancer Immunotherapy
Theresa LaVallee, PhD – Parker Institute for Cancer Immunotherapy
2:50 p.m. Infectious Disease and Biomarkers I
David Kaufman, MD, PhD – Bill & Melinda Gates Medical Research Institute
3:10 p.m. Infectious Disease and Biomarkers II: Viral Biomarker Discovery using CyTOF
Holden T. Maecker, PhD – Stanford University Medical Center
3:30 p.m. Biomarkers in Authoimmunity
Zoe Quandt, MD – University of California, San Francisco
3:50 p.m. Panel Discussion
4:50 p.m. Closing Remarks
Lisa H. Butterfield, PhD – University of Pittsburgh