|
View Enduring Materials
Enduring materials are now open access.
 Indicates this content is not available on-demand.
|
|
Thursday, April 21
*All times are Pacific Daylight Time.
|
|
Registration & Breakfast
7–8 a.m.
|
|
Opening Remarks
8–8:10 a.m.
|
|
8 a.m.
|
Opening Remarks
|
Keynote Address
8:10–9:10 a.m.
|
| 8:10 a.m. |
Targeting The Tissue and Tumor Microenvironment and Microbiome To Promote Health and End Cancer
Jennifer A. Wargo, MD, MMSc – The University of Texas MD Anderson Cancer Center
|
|
Session I: Visualizing the TME
9:10–10:50 a.m.
|
|
9:10 a.m.
|
Cancer Rearranges the Rules in Tissue Building Blocks: A New Class of Targets for Therapy?
Garry Nolan, PhD – Stanford University
|
|
9:35 a.m.
|
Decoding the Lung Cancer Immune Microenvironment Using Spatially-resolved Multiplexed Tissue Analysis
Kurt Schalper, MD, PhD – Yale University
|
|
10 a.m.
|
Integrating Tumor Heterogeneity for Radiomics Guided Radio-immunotherapy?
Eric Deutsch, MD, PhD – Gustave Roussy Cancer Campus
|
|
10:25 a.m.
|
Autofluorescence Imaging of Immune Cell Metabolism
Melissa Skala, PhD – Morgridge Institute for Research
|
|
10:50–11:05 a.m.
|
Break
|
|
Session II: Metabolism: Nutrient Availability and Competition
11:05 a.m.–12:35 p.m.
|
|
11:05 a.m.
|
Impact of Extracellular Nutrients on Tumor Biology
Matt Vander Heiden, MD, PhD – Koch Institute at MIT
|
|
11:30 a.m.
|
Metabolic Alterations in the Tumor-Draining Lymph Node-Niche
Angela Riedel, PhD – University of Würzburg
|
|
11:55 a.m.
|
Dissecting the Role of Metabolites in the Tumor Microenvironment
Marcia C. Haigis, PhD – Harvard Medical School
|
|
12:20 p.m.
|
(O5) Lactate uptake through MCT11, a novel monocarboxylate transporter, enforces dysfunction in terminally exhausted T cells
Ronal Peralta, BS – University of Pittsburgh
|
|
Lunch
12:35–2:05 p.m.
|
|
Session III: Pediatric Tumors
2:05–3:35 p.m.
|
|
2:05 p.m.
|
Osteosarcoma
Christian M. Capitini, MD – University of Wisconsin-Madison
|
|
2:30 p.m.
|
Immune Landscape of Rhabdoid Tumors: Non-Genetic Mechanisms of Tumor Immunogenicity
Eliane Piaggio, MD – Institut Curie
|
|
2:55 p.m.
|
Modulating the Metastatic Microenvironment for Therapeutic Gain
Rosandra (Rosie) Kaplan, MD – National Cancer Institute, NIH
|
|
3:20 p.m.
|
(O2) Spatiotemporal co-dependency between macrophages and exhausted CD8+ T cells in cancer
Kelly Kersten, PhD – University of California San Francisco
|
|
3:35–3:50 p.m.
|
Break
|
|
Session IV: Oncogenomics and Immunology
3:50–5:20 p.m.
|
|
3:50 p.m.
|
Immune and Malignant Cell Phenotypes of Ovarian Cancer are Determined by Distinct Mutational Processes
Sohrab Shah, PhD – Memorial Sloan Kettering Cancer Center
|
|
4:15 p.m.
|
Effects of Germline Genetics on the TME
Davide Bedognetti, MD, PhD – Sidra Medicine
|
|
4:40 p.m.
|
Targeting the Interaction of Oncogenic Signaling with Immunity in Breast Cancer
Sangeetha Reddy, MD, MSci – University of Texas Southwestern
|
|
5:05 p.m.
|
(O1) Characterization of molecular and spatial diversity of macrophages in hepatocellular carcinoma
Pauline Hamon, PhD – Icahn School of Medicine, Mount Sinai
|
|
Poster Session
5:20–6:20 p.m.
|
|
6:20 p.m.
|
Adjourn
|