Here, the authors summarize the 2012 SITC Primer, reviewing past, present, and emerging immunotherapeutic approaches for the treatment of cancer—including targeting innate versus adaptive immune components; targeting and/or utilizing dendritic cells and T cells; the role of the tumor microenvironment; and immune checkpoint blockade.Authors: Timothy J. Harris and Charles G. DrakePublished as a review in the Journal for ImmunoTherapy of Cancer (2013) 1:12.#SITCPublication