Michael T. Lotze, MD is Professor of Surgery, Immunology, and Bioengineering; Director of the DAMP Laboratories at the UPMC Hillman Cancer Center. His research work includes modern immunotherapy and gene therapy, dendritic cell, T cell, and cytokine therapies, and investigation of the role of mitochondria, metabolism, and unscheduled cell death in cancer. Dr. Lotze has worked in the field of immunology and clinical medicine for over 30 years and has had the opportunity to personally review and advance the work of individuals developing translational research, particularly within cancer. Dr. Lotze is a clinician scientist who has spent the last decade assembling teams to work on the extraordinary problem of pancreatic cancer, renal cancer, and lung cancer. He is a long-time SITC enthusiast, attending his first meeting in Williamsburg, presiding over the Society in 1998, and launching both the Primer on Tumor Immunology as well as the SITC Clinical Immuno-Oncology Network to advance the most rigorous and robust clinical protocols in immunotherapy of cancer. Dr. Lotze is the co-inventor of 10 patents in dendritic cell vaccines and antigen discovery, 13 patents in tumor infiltrating lymphocyte therapy (while at Iovance), additional patents at Nurix Therapeutics where he served as Chief Cell Therapy Officer 2020-2023. He is an award-winning NCI-trained scientist (1978-1990), the inaugural Director of Surgical Oncology at Pitt (1990-2000), former Vice President of Research at GlaxoSmithKline (2001), founding director of the UPCI Academy, former Chief Scientific Officer at Lion/Iovance Biotherapeutics, former CCO at Nurix Therapeutics, and innovative educator as a prolific clinician-scientist/tumor immunologist with over 500 publications and several books.
Read a recent interview with Dr. Lotze.