2021 Targets for Cancer Ummnotherapy: A Deep Dive Seminar Series

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SEMINAR 1 – TGF-beta: A Deep Dive in Cancer Immunotherapy Targets

• Date of Live Event: 2–4 p.m. EDT on May 26, 2021
• Co-chairs:
  • James L. Gulley, MD, PhD, FACP – National Cancer Institute
  • Shannon J. Turley, PhD – Genentech, Inc.
• Faculty:
  • Mary Helen Barcellos-Hoff, PhD – University of California San Francisco
  • James L. Gulley, MD, PhD, FACP – National Cancer Institute
  • Ming O. Li, PhD – Memorial Sloan-Kettering Cancer Center
  • Dean Sheppard, MD – University of California San Francisco
  • Shannon J. Turley, PhD – Genentech, Inc.

SEMINAR 2 – The TIGIT Pathway: A Deep Dive in Cancer Immunotherapy Targets

• Date of Live Event: 2–4 p.m. EDT on June 29, 2021
• Co-chairs:
  • Jane Grogan, PhD – Graphite Bio
    
  • Alan J. Korman, PhD – Vir Biotechnology
• Faculty:
  • Dhan Chand, PhD – Agenus
  • David A. Hafler, MD – Yale University
  • Ira Mellman, PhD – Genentech, Inc.
    
  • Eran Ophir, PhD – Compugen Ltd.

SEMINAR 3 – IL-2 Variants and IL-15: A Deep Dive in Cancer Immunotherapy Targets

• Date of Live Event: 4:30–6:30 p.m. EDT on July 19, 2021
• Co-chairs:
  • Rafi Ahmed, PhD – Emory University
  • Michael B. Atkins, MD – Georgetown Lombardi Comprehensive Cancer Center
  • Warren J. Leonard, MD – Laboratory of Molecular Immunology, NHLBI
• Faculty:
  • Michael B. Atkins, MD – Georgetown Lombardi Comprehensive Cancer Center
  • Warren J. Leonard, MD – Laboratory of Molecular Immunology, NHLBI
  • Jamie B. Spangler, PhD – Johns Hopkins University
  • Thomas A. Waldmann, MD – National Cancer Institute, National Institutes of Health

SEMINAR 4 – Adenosine: A Deep Dive in Cancer Immunotherapy Targets

• Date of Live Event: 11:30 a.m.–1:30 p.m. EDT on Aug. 24, 2021
• Co-chairs:
  • Lawrence Fong, MD – University of California San Francisco
  • Aung Naing, MD, FACP – The University of Texas MD Anderson Cancer Center
• Faculty:
  
  • Robert D. Leone, MD – Johns Hopkins Hospital
  • Jason J. Luke, MD, FACP – University of Pittsburgh Medical Center Hillman Cancer Center
    
  • Michail Sitkovsky, PhD – Northeastern University College of Medicine

SEMINAR 5 – Macrophage Biology for Anti-Tumor Immunity: A Deep Dive in Cancer Immunotherapy Targets

• Date of Live Event: 10:30 a.m.–12:30 p.m. EDT on Oct. 7, 2021
• Co-chairs:
  • Miriam Merad, MD, PhD – Icahn School of Medicine at Mount Sinai
  • Carla V. Rothlin, PhD – Yale School of Medicine
• Faculty:
  • Brian Brown, PhD – Icahn School of Medicine at Mount Sinai
  • Hind Medyouf, PhD – Georg-Speyer-Haus
  • Maria Casanova-Acebes, PhD – Centro Nacional de Investigaciones Oncológicas

SEMINAR 6 – The 4-1BB Pathway: A Deep Dive in Cancer Immunotherapy Targets

• Date of Live Event: 3:30–5:30 p.m. EDT on Oct. 21, 2021
• Co-chairs:
  • Carl H. June, MD – University of Pennsylvania
  • Ignacio Melero, MD, PhD – FIMA, Clinica Universidad de Navarra
• Faculty:
  • Christian Klein, PhD – Roche Innovation Center Zurich
  • Byoung S. Kwon, PhD – Eutilex
  • Ignacio Melero, MD, PhD – FIMA, Clinica Universidad de Navarra
  • Michael Milone, MD, PhD – University of Pennsylvania

SEMINAR 7 – T cell Functional States: A Deep Dive in Cancer Immunotherapy Targets

• Date of Live Event: 4:30–6:30 p.m. EST on Nov. 18, 2021
• Co-chairs:
  • Andrea Schietinger, PhD – Memorial Sloan Kettering Cancer Center
  • E. John Wherry, PhD – University of Pennsylvania
• Faculty:
  
  • Ananda W. Goldrath, PhD – University of California, San Diego
  • Evan W. Newell, PhD – Fred Hutchinson Cancer Research Center
  • Daniela S. Thommen, MD, PhD – The Netherlands Cancer Institute

SEMINAR 8 – T cell Selection for Adoptive Cell therapy: A Deep Dive in Cancer Immunotherapy Targets

• Date of Live Event: 11:30 a.m.–1:30 p.m. EST on Jan. 25, 2022
• Co-chairs:
  
  • Cara Haymaker, PhD – The University of Texas MD Anderson Cancer Center
  • Cassian Yee, MD – The University of Texas MD Anderson Cancer Center
• Faculty:
  • Marcela V. Maus, MD, PhD – Massachusetts General Hospital
  • Chrystal M. Paulos, PhD – Winship Cancer Institute at Emory University
  • Stanley R. Riddell, MD – Fred Hutchinson Cancer Research Center

This series will serve as an excellent resource for all stakeholders interested in expanding their knowledge in computation immune-oncology. Specifically, early career scientists who want to further their training in computational immuno-oncology, as well as more senior career individuals who want to implement these techniques for the first time will greatly benefit from the series.

Learning Objectives

A key goal of this training program is to ensure participants remain on the cutting edge of computational immuno-oncology, to increase the participants’ awareness of the NCI-supported Cancer Moonshot Immunotherapy Networks, to enhance scientific engagements between the Cancer Moonshot^SM Immunotherapy Networks and the broader cancer immunotherapy community, and to fulfill the Blue Ribbon Panel goal of acceleration of progress in cancer research.

Series Organizers

• Kellie N. Smith, PhD – Johns Hopkins School of Medicine
  • Big Data and Data Sharing Committee, Chair
• Song Liu, PhD – Roswell Park Comprehensive Cancer Center, NCI Cancer Moonshot IOTN & DRSN
  • Big Data and Data Sharing Committee, Co-Chair
• Alan Hutson, PhD – Roswell Park Comprehensive Cancer Center, NCI Cancer Moonshot IOTN & DRSN
  • Big Data and Data Sharing Committee, Immediate Past Chair
• Carsten Krieg, PhD – Medical University of South Carolina
  • Big Data and Data Sharing Committee, Member

Basic, clinical and translational researchers in academia and industry and members of the investment community.