On October 16, 2025, the Society for Immunotherapy of Cancer (SITC) in partnership with the National Cancer Institute (NCI) held the eighth computational immuno-oncology webinar of series 5. In this webinar, attendees explored the transformative potential of liquid biopsy approaches in cancer characterization, residual disease tracking and therapy response monitoring. Focusing on analyses of circulating tumor DNA (ctDNA), they reviewed how liquid biopsies provide unique insights into tumor dynamics and enable clinicians and researchers to make data-driven decisions that improve patient outcomes. The webinar also covered a comprehensive assessment of current and emerging technologies together with computational methodologies developed for analyses of ctDNA sequencing data. It ended with a discussion on clinical integration, focusing on cancer immunotherapy and discussed where we stand with implementation of liquid biopsies in ctDNA molecular response-adaptive clinical trials for patients receiving immunotherapy.
View the webinar for free on-demand HERE.