Dr. Jaffee is an internationally recognized expert in cancer immunology and pancreatic cancer. She is Deputy Director of the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Co-Director of the Skip Viragh Pancreatic Cancer Center and Associate Director of the Bloomberg Kimmel Institute for Cancer Immunotherapy, and the inaugural director of the Convergence Institute for Integrating Technologies and Computational Sciences at Johns Hopkins. Her research focus is on developing novel immunotherapies for the treatment and prevention of pancreatic cancer. Her recent work has focused on developing novel biomarker driven immunotherapy clinical trials to dissect the complex inflammatory signals within the tumor microenvironment. Through collaborations with computational biologists, her team has identified a number of immune suppressive signals that regulate pancreatic cancer development and progression.
Dr. Jaffee is a Past President of AACR. She has served on many committees at the National Cancer Institute, including the National Cancer Advisory Board as member and Chair, and as one of 3 co-chairs of the Biden Moonshot Blue Ribbon Panel which identified high impact research priorities for the NCI. She currently serves as Chief Medical Advisor to the Lustgarten Foundation for Pancreatic Cancer Research. Dr. Jaffee is a member of the National Academy of Medicine, a Fellow of the American College of Physicians, a Fellow of American Association for the Advancement of Science, a Fellow of the SITC Academy of Immuno-Oncology and a Fellow of the AACR Academy. Most recently, she was appointed chair of President Biden’s Cancer Panel.