SITC Immune Exclusion Virtual Summit

SITC Immune Exclusion Virtual Summit 

09-22-2023 12:49

Program Summary

The SITC will host the Immune Exclusion Virtual Summit on Monday, Sept. 18, 2023, from 12–5 p.m. EDT. The summit is a free, public event that features invited speakers, expert panel discussions, and attendee question and answer periods. The multi-stakeholder virtual summit will feature over 25 panelists representing academic research and industry from around the world. The SITC Immune Exclusion Virtual Summit will highlight the latest research on the mechanisms of immune exclusion among different tumor types and molecular tools available to study immune-excluded tumors. Topics to be addressed at the summit include the pathology and clinical and therapeutic implications of immune exclusion, mechanisms of immune exclusion, diagnostics for immune exclusion, and current therapeutic strategies for immune exclusion.

The SITC Immune Exclusion Virtual Summit will highlight the current understanding of molecular mechanisms underlying immune exclusion and the tools available to study immune-excluded tumors. This open-door virtual educational event will present the state of the field and feature participation of invited stakeholders involved in this field, including clinicians, pathologists, and researchers from academia and industry.

Problem Statement

Immune-excluded tumors, characterized by lymphocytes that surround the tumor but fail to penetrate it, represent about one-third of cancers. The mechanisms underlying immune exclusion remain unclear but may include some combination of physical and/or functional barriers that prevent infiltration of immune cells into the tumor. Defining the unique biology of immune-excluded tumors and elucidating the mechanisms underlying immune exclusion will identify new strategies for cancer immunotherapy, especially in the field of adoptive cellular therapy.

Summit Goals and Objectives

The primary objective of the SITC Immune Exclusion Virtual Summit is to elucidate the molecular mechanisms of immune exclusion in distinct tumor types. Secondary goals include exploring how exclusion biology manifests in different tumor types; reviewing molecular tools available to study immune-excluded tumors; and defining the unique biology of immune-excluded cancers relative to immune-infiltrated and immune-desert tumors.

Summit Organizers

Leisha A. Emens, MD, PhD Ankyra Therapeutics

Dan Chen, MD, PhD – Engenuity Life Sciences

Davide Bedognetti, MD, PhD Kite Pharma

Francesco Marincola, MD Sonata Therapeutics

Sara Pai, MD, PhD Yale University School of Medicine

Sarah Warren, PhD Kite Pharma

Christine Moussion, PhD Genentech

You can find more program details and the summit agenda here.

Statistics
0 Favorited
51 Views
26 Files
0 Shares
17 Downloads

 Video
Attachment(s)
mp4 file
Full Video - Immune Exclusion Virtual Summit   2.54 GB   1 version
Uploaded - 09-22-2023
Meeting: Immune Exclusion Virtual Summit; Date: September 18, 2023
mp4 file
A Pathology Perspective (Koeppen)   190.58 MB   1 version
Uploaded - 01-31-2024
Meeting: Immune Exclusion Virtual Summit; Date: September 18, 2023
mp4 file
Video - Quantifying immune phenotypes in cancer pathology...   115.32 MB   1 version
Uploaded - 01-31-2024
Meeting: Immune Exclusion Virtual Summit; Speaker: Jakob Kather, MD, MSc; Date: September 18, 2023
pdf file
Presentation - Quantifying immune phenotypes in cancer pa...   4.17 MB   1 version
Uploaded - 01-31-2024
Meeting: Immune Exclusion Virtual Summit; Speaker: Jakob Kather, MD, MSc; Date: September 18, 2023
mp4 file
Video - Defining and Understanding Resistance to Checkpoi...   86.61 MB   1 version
Uploaded - 01-31-2024
Meeting: Immune Exclusion Virtual Summit; Speaker: Ryan Sullivan, MD; Date: September 18, 2023
pdf file
Presentation - Defining and Understanding Resistance to C...   2.77 MB   1 version
Uploaded - 01-31-2024
Meeting: Immune Exclusion Virtual Summit; Speaker: Ryan Sullivan, MD; Date: September 18, 2023
mp4 file
Video - Neoantigen-Specific Cancer Vaccine Development (J...   139.32 MB   1 version
Uploaded - 01-31-2024
Meeting: Immune Exclusion Virtual Summit; Date: September 18, 2023
mp4 file
Video - Addressing Mechanical and Biologic Features of IO...   117.24 MB   1 version
Uploaded - 01-31-2024
Meeting: Immune Exclusion Virtual Summit; Speaker: Steven C. Katz, MD, FACS; Date: September 18, 2023
pdf file
Presentation - Addressing Mechanical and Biologic Feature...   9.29 MB   1 version
Uploaded - 01-31-2024
Meeting: Immune Exclusion Virtual Summit; Speaker: Steven C. Katz, MD, FACS; Date: September 18, 2023
mp4 file
pMMR vs dMMR tumors (Chalabi)   87.29 MB   1 version
Uploaded - 01-31-2024
Meeting: Immune Exclusion Virtual Summit; Date: September 18, 2023
mp4 file
Video - Setting the Stage Panel and Q&A Session   592.91 MB   1 version
Uploaded - 01-31-2024
Meeting: Immune Exclusion Virtual Summit; Date: September 18, 2023
pdf file
Presentation - Overview of the Current Mechanistic Unders...   1.28 MB   1 version
Uploaded - 01-31-2024
Meeting: Immune Exclusion Virtual Summit; Author: Sara Isabel Pai, MD, PhD, FACS; Date: September 18, 2023
mp4 file
Mechanisms of Immune Exclusion   930.97 MB   1 version
Uploaded - 01-31-2024
Meeting: Immune Exclusion Virtual Summit; Date: September 18, 2023
pdf file
Presentation - Mechanisms and consequences of pancreatic ...   965 KB   1 version
Uploaded - 01-31-2024
Meeting: Immune Exclusion Virtual Summit; Speaker: Mara Sherman, PhD; Date: September 18, 2023
pdf file
Presentation - Immune exclusion as a function of tumor ge...   1.00 MB   1 version
Uploaded - 01-31-2024
Meeting: Immune Exclusion Virtual Summit; Speaker: Dmitriy Zamarin, MD, PhD; Date: September 18, 2023
pdf file
Presentation - Myeloid cells, NETs and arginase in pancre...   2.36 MB   1 version
Uploaded - 01-31-2024
Meeting: Immune Exclusion Virtual Summit; Speaker: Vincenzo Bronte, MD; Date: September 18, 2023
mp4 file
Tools to Understand Immune Exclusion   1.15 GB   1 version
Uploaded - 01-31-2024
Meeting: Immune Exclusion Virtual Summit; Date: September 18, 2023
pdf file
Presentation - Spatial Biology as a Tool to Reveal Mechan...   14.68 MB   1 version
Uploaded - 01-31-2024
Meeting: Immune Exclusion Virtual Summit; Speaker: Carlo Bifulco, MD; Date: September 18, 2023
mp4 file
Diagnostics for Immune Exclusion   681.57 MB   1 version
Uploaded - 01-31-2024
Meeting: Immune Exclusion Virtual Summit; Date: September 18, 2023
pdf file
Focus on histopathology (Taube)   1.22 MB   1 version
Uploaded - 01-31-2024
Meeting: Immune Exclusion Virtual Summit; Speaker: Janis Taube, MD; Date: September 18, 2023
pdf file
Molecular imaging with PET (de Vries)   1.87 MB   1 version
Uploaded - 01-31-2024
Meeting: Immune Exclusion Virtual Summit; Speaker: Elisabeth de Vries, MD, PhD; Date: September 18, 2023
pdf file
B cells and TLS add to the understanding (Fridman)   3.31 MB   1 version
Uploaded - 01-31-2024
Meeting: Immune Exclusion Virtual Summit; Speaker: Wolf Fridman, MD, PhD; Date: September 18, 2023
mp4 file
Therapeutic Strategies for Immune Exclusion   1.24 GB   1 version
Uploaded - 01-31-2024
Meeting: Immune Exclusion Virtual Summit; Date: September 18, 2023
pdf file
Therapeutic approaches to ECM (Powell)   1.07 MB   1 version
Uploaded - 01-31-2024
Meeting: Immune Exclusion Virtual Summit; Speaker: Daniel Powell, PhD; Date: September 18, 2023
pdf file
Chemotherapy and radiation (Young)   972 KB   1 version
Uploaded - 01-31-2024
Meeting: Immune Exclusion Virtual Summit; Speaker: Kristina Young, MD, PhD; Date: September 18, 2023
pdf file
specialized blood vessels for lymphocyte entry into tumo...   1.83 MB   1 version
Uploaded - 01-31-2024
Meeting: Immune Exclusion Virtual Summit; Speaker: Jean-Philippe Girard, PhD; Date: September 18, 2023

Related Entries and Links

No Related Resource entered.