The Society for Immunotherapy of Cancer (SITC) hosted Session 207e during the 39th Annual Meeting & Pre-Conference Programs on Saturday, November 9, 2024. Available here are the presentation slides and video from “Session 207e: Modulating the Tumor Vasculature to Improve Immunotherapy” as permitted by presenters.
Edda Sciutto, PhD – Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico
Sabina Signoretti, MD – Brigham and Women's Hospital
Blood and lymphatic vessels are essential for oxygen and nutrient delivery, removal of waste products, and control of immune responses to maintain normal tissue homeostasis. The rapid formation of tumor tissues requires an accelerated vascularization process that leads to a dysfunctional blood and lymphatic vessel network. This abnormal tumor vasculature contributes to the creation of a hypoxic and acidic tumor microenvironment, which facilitates cancer cells growth and metastatic dissemination, and also limits the infiltration of immune cells and their anti-tumor activity.
New approaches aimed at modulating the tumor vasculature represent a promising strategy to maximize patient response to cancer treatments. This session will focus on exciting findings obtained by targeting blood and lymphatic vessels to increase the efficacy of immunotherapy in various cancer types.
To view the entire program schedule (including presenter permission to post) please click here.
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