The Society for Immunotherapy of Cancer (SITC) hosted Session 207b during the 38th Annual Meeting & Pre-Conference Programs on Saturday, November 4, 2023. Available here are the presentation slides and video from “Session 207b: Metabolism and the Immune Response to Cancer” as permitted by presenters.
Ping-Chih Ho, PhD – Ludwig Cancer Center
Robert Leone, MD – Johns Hopkins University
Work over the past several decades has underscored that cancers and immune cells can be characterized by distinct and specific metabolic pathways and nutrient requirements. As such, the interplay between the metabolic requirements of tumor-responsive immune cells and existing metabolic conditions, both within the tumor microenvironment and systemically, plays a critical role in determining the nature and extent of the anti-tumor response. In fact, metabolic challenges can be understood as checkpoints to immune response, and recent work has highlighted the principle that metabolic vulnerabilities in cancer can be targeted to enhance the immune response. Speakers in this session will highlight new insights into this field from a number of perspectives, including the role of systemic metabolism on the anti-tumor immune response, specific metabolic features of cancer and how these programs locally influence the immune response, and lastly, metabolic adaptations of cancer to therapeutic intervention.
To view the entire program schedule (including presenter permission to post) please click here.
SITC 2023 Annual Meeting: Saturday, November 401:28:14