The Society for Immunotherapy of Cancer (SITC) hosted Session 106a during the 38th Annual Meeting & Pre-Conference Programs on Friday, November 3, 2023. Available here are the presentation slides and video from “Session 106a: Mechanisms of Resistance to Immune Checkpoint Inhibitors” as permitted by presenters.
Harriet Kluger, MD – Yale University
Arlene Sharpe, MD, PhD, FAIO – Harvard Medical School
While immune checkpoint inhibitors have resulted in prolonged responses and cures in subsets of patients, many do not respond while others may develop resistance over time. Diverse mechanisms of resistance have been identified, including cellular and molecular immune-suppressive elements. In this session we will discuss recently described mechanisms affecting T cells and other key cells in the tumor microenvironment, cellular screens that will inform future studies and novel machine learning methods to decipher the complex interactions that lead to resistance.
To view the entire program schedule (including presenter permission to post) please click here.
SITC 2023 Annual Meeting: Friday, November 301:41:27