SITC corporate memberships provide organizations vested in cancer immunotherapy and cancer research a forum to address common issues impacting the field with the goal of improving cancer patient outcomes. In 2024, SITC corporate members gathered with leaders from SITC and the FDA to discuss Project Optimus and accelerated approval for metastatic disease and connecting these mechanisms to potential use for cellular therapies and relevant endpoints such as objective response rate, progression free survival, and (landmark) overall survival. Additionally, the group discussed perioperative disease and its relevancy to endpoints such as pathologic complete response and circulating tumor DNA.