Due to advances in cancer immunotherapy, including positive results from clinical trials testing new agents and combinations, emerging new technologies for measuring aspects of immunity, and novel candidate biomarkers from early phase trials, the SITC Immune Biomarkers Task Force has reconvened to review state of the art technologies, identify current hurdles to further success and to make recommendations to the field.
Topics being addressed by individual working groups include:
In the video below, published by OncLive, watch as SITC President Dr. Lisa Butterfield discusses the Immune Biomarkers Task Force.
View current and past Task Force members via the links below:
Validation of Biomarkers to Predict Response to Immunotherapy in Cancer (two-part white paper) Journal for ImmunoTherapy of Cancer, November 2016
Novel Technologies and Emerging Biomarkers for Personalized Cancer Immunotherapy Journal for ImmunoTherapy of Cancer, January 2016
Systematic Evaluation of Immune Regulation and Modulation Journal for ImmunoTherapy of Cancer, March 2017
Identifying baseline immune-related biomarkers to predict clinical outcome of immunotherapy Journal for ImmunoTherapy of Cancer, May 2017
Click here to view a complete list of current and past published Immune Monitoring Technology Primers in the Journal for ImmunoTherapy of Cancer (JITC).
SITC/iSBTc Cancer Immunotherapy Biomarkers Resource Document: Online resources and useful tools – a compass in the land of biomarker discovery Journal of Translational Medicine, September 2011
Recommendations from the iSBTc-SITC/FDA/NCI Workshop on Immunotherapy Biomarkers Clinical Cancer Research, May 2011
Immuno-Oncology Biomarkers 2010 and Beyond: Perspectives from the iSBTc/SITC Biomarker Taskforce Journal of Translational Medicine, December 2010
A Systematic Approach to Biomarker Discovery; Preamble to "the iSBTc-FDA Taskforce on Immunotherapy Biomarkers" Journal of Translational Medicine, December 2008
NCI/CCR and SITC co-sponsored a 2016 Biomarkers meeting to review the state of the art, discuss current hurdles to further success, and consider recommendations to move the field forward.
The main goals were to provide updated information to a wide audience and solicit stakeholder participation in promoting successful immune biomarker research.
A report of this meeting was published in the Journal for ImmunoTherapy of Cancer (JITC) in March 2017. Click here to read Immunotherapy Biomarkers 2016: Overcoming the Barriers. Also, to learn more about the event and its schedule, click here.
It was great seeing old friends again and meeting new ones at the 32 nd Annual Meeting & Pre-Conference Programs in National Harbor! We appreciate all who joined SITC for our most successful Annual Meeting yet and hope you had a great time learning, ...
The cited 2017 case report states " The restoration of the cellular immune response against tumor cells through PD-1 blockade and CRLA-4 blockade have recently been shown to be associated with increased survival in metastatic RCC developed from native ...
This is an interesting subject to me since a few years back we published a study in the American Journal of Transplantation that showed blocking mTOR with a low dose of rapamycin enhanced anti-tumor activity while suppressed allogeneic response in ...
Thanks for the comments. He is to start TKI, but is also asking about other ideas. There are multiple non-Oncologist physicians in family who are feeding him questions and idea. I'm sure I won't be his only opinion. Bill ------------------------------ ...
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