The SITC Sparkathon – Emerging Leaders, Igniting Innovation is an exciting opportunity for early career professionals seeking to participate in new research that contributes to the cancer immunotherapy field and the society as a whole.
Following an application process, a group of 30 emerging leaders will explore the critical hurdles that have challenged this field for years. Once projects have been determined, teams will formulate plans to solve the major issues. Participants will have access to leadership experts who will assist teams in developing their proposals for successful implementation.
Projects will be presented to a panel of SITC leaders who will select the top proposals for implementation.
But first ...
Before SITC can open the Sparkathon application process and attempt to make a large leap forward in research, the society must meet its goal to raise $600,000. An anonymous donor has pledged to DOUBLE all donations made to the Forward Fund, meaning the society has been challenged to raise $300,000 over the next two years ($150,000 per year) for this special initiative.
Now is the time to ignite the Sparkathon!
If SITC reaches its goal, $600,000 will help create a unique opportunity for the society’s early career professionals to tackle the biggest hurdles facing the future of the research. Consider making a pledge or contribution to the Forward Fund now and make twice the impact on the society and a lasting difference for the future of cancer immunotherapy.
To have your SITC Sparkathon donation doubled, text SPARK to 50555 to donate $25 or click the button below to contribute online.
As a 501(c)(3) organization, donations made to SITC are tax deductible as a charitable contribution to the extent allowed by law.
This may be due to an alternate immune checkpoint, CD200 (OX2) checkpoint blockade. The immuneosuppressive CD200 protein shuts down the immune system through multiple mechanisms (Xiong et al, 2016). We demonstrated that human glioblastoma in the top ...
While I agree with Stephanie's detailed account, simply put checkpoint molecules are a signature of exhausted/ chronically stimulated lymphocytes and therefore serves as a feedback mechanism to mitigate the immune activation from entering an overdrive ...
Hi Stephanie many thanks for your ample reply. It makes sense indeed in order to secure self-antigens. However, is immune system evasion by means of immune checkpoint a matter of quality or quantity? I mean is there a cutoff for "normal"CTLA4, PD1 levels ...
The expression and regulation of immune checkpoints is an area of active investigation. In answer to your question regarding whether healthy tissues express immune checkpoint inhibitors in the steady state they absolutely do! Immune ...
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