SITC Archive Library

Workshop on Intratumoral Immunomodulation: Session 4: Intratumoral Oncolytic Modulators 

10-16-2019 14:47

The Society for Immunotherapy of Cancer (SITC) hosted the "Workshop on Intratumoral Immunomodulation" during the SITC 2019 Annual Meeting on November 7, 2019. Available here are the presentation slides and video from "Session 4: Intratumoral Oncolytic Modulators."

Program Summary

Immunotherapy treatments inherently rely on the presence of immune cells, both systemic and localized to the tumor microenvironment. Immunologically “hot” tumors, such as melanoma, have demonstrated enhanced responses to immunotherapy treatments; however, many tumors are “cold”, lacking the necessary immune components for a successful treatment. Many techniques, including radiotherapy, synthetic immunomodulators, oncolytic viruses, and certain systemic treatments, have been shown to manipulate the immune status of the treated tumor microenvironment, and even those tumor sites elsewhere in the body (abscopal effects). Such manipulations can increase the presence of desirable immune infiltrates and potentially lead to favorable treatment outcomes. In this workshop, the current status of intratumoral immunomodulation was presented and future directions for the field discussed, along with their implications for current and forthcoming immunotherapy treatments.

Program Organizers

  • Nina Bhardwaj, MD, PhD – The Tisch Cancer Institute at The Icahn School of Medicine at Mount Sinai
  • Adi Diab, MD – The University of Texas MD Anderson Cancer Center

To view the entire program schedule (including presenter permission to post) please click here.

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Attachment(s)
pdf file
"The Role of T-VEC and Other Oncolytic Viruses in Priming...   5.27 MB   1 version
Uploaded - 12-12-2019
Meeting: SITC 34th Annual Meeting; Workshop on Intratumoral Immunomodulation; Session 4: Intratumoral Oncolytic Modulators; Presenter: Howard L. Kaufman, MD, FACS – Replimune Group, Inc.; Date: November 7, 2019
mp4 file
"The Role of T-VEC and Other Oncolytic Viruses in Priming...   449.12 MB   1 version
Uploaded - 12-17-2019
Meeting: SITC 34th Annual Meeting; Workshop on Intratumoral Immunomodulation; Session 4: Intratumoral Oncolytic Modulators; Presenter: Howard L. Kaufman, MD, FACS – Replimune Group, Inc.; Date: November 7, 2019
pdf file
"Development of Multiplex Oncolytic Viruses" - Presentati...   4.51 MB   1 version
Uploaded - 12-12-2019
Meeting: SITC 34th Annual Meeting; Workshop on Intratumoral Immunomodulation; Session 4: Intratumoral Oncolytic Modulators; Presenter: John Bell, PhD – University of Ottawa; Date: November 7, 2019
mp4 file
"Development of Multiplex Oncolytic Viruses" - Video   422.59 MB   1 version
Uploaded - 12-18-2019
Meeting: SITC 34th Annual Meeting; Workshop on Intratumoral Immunomodulation; Session 4: Intratumoral Oncolytic Modulators; Presenter: John Bell, PhD – University of Ottawa; Date: November 7, 2019

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