On behalf of SITC, we are pleased to announce the publication of a new manuscript titled, “ A SITC Vision: Adapting Clinical Trials to Accelerate Drug Development in Cancer Immunotherapy ” available now in the Journal for ImmunoTherapy of Cancer ( JITC ). This manuscript is the second in a JITC Special Series — The Next Wave of Immuno-oncology: A Roadmap from the Society for Immunotherapy of Cancer, which outlines the current state of the field, ...
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INSIDE THIS ISSUE: Letter from the Editor | JITC Editor Picks | Popular Archive Articles Letter from the Editor Dear Readers, We find ourselves amid a rather unsettling period for scientists and cancer clinicians in the nation, and by reflection, around the world. We join our deeply concerned colleagues at both the US National Institutes of Health (NIH) and the National ...
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An addendum to the " Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of melanoma " is now available. In accordance with the Institute of Medicine’s Standards for Developing Trustworthy Clinical Practice Guidelines (CPGs), SITC CPGs undergo periodic evaluation to assess if new evidence necessitates modifications to recommendations, treatment algorithms, or other guideline content. This is ...
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Manuscript Title: Where's the data? Delayed and chronic irAE management and surveillance after cessation of immune checkpoint inhibitors: Expert insights from SITC on survivorship care and the need for long-term data Draft Manuscript Summary Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy, offering durable responses and prolonged survival. However, these therapies also present unique challenges, particularly ...
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The Society for Immunotherapy of Cancer (SITC) is seeking volunteers to join the Cancer Immunotherapy Guidelines (CIG) Oversight Committee, which plays a key role in guiding the society’s clinical practice guideline development and dissemination strategy. The CIG Oversight Committee oversees the development and updating of new and existing cancer immunotherapy clinical practice guidelines (CPGs) by setting the policies and protocols for SITC guidelines ...
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An update to " Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of head and neck squamous cell carcinoma ” is now available. In accordance with the Institute of Medicine’s Standards for Developing Trustworthy Clinical Practice Guidelines (CPGs), SITC CPGs undergo periodic evaluation to assess if new evidence necessitates modifications to recommendations, treatment algorithms, or other guideline ...
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The Society for Immunotherapy of Cancer is pleased to share a collaborative effort between the HHS Assistant Secretary for Technology Policy/Office of the National Coordinator for Health Information Technology (ASTP), the National Cancer Institute (NCI), and Food and Drug Administration (FDA) focused on the release of the USCDI+ Cancer Immune-related Adverse Events (irAE) draft dataset. The goal of this data set is to enhance the accuracy and reliability ...
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An update to " Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of urothelial cancer " is now available. In accordance with the Institute of Medicine’s Standards for Developing Trustworthy Clinical Practice Guidelines (CPGs), SITC CPGs undergo periodic evaluation to assess if new evidence necessitates modifications to recommendations, treatment algorithms, or other guideline content. ...
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The Society for Immunotherapy of Cancer (SITC) is pleased to announce the publication of a review manuscript titled " Biomarker development for PD-(L)1 axis inhibition: a consensus view from the SITC Biomarkers Committee ." Understanding the mechanisms that drive PD-L(1) inhibitor resistance and the development of predictive biomarkers is key in advancing the field of immunotherapy. To address this significant hurdle in the field, SITC convened ...
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The Society for Immunotherapy of Cancer (SITC) is pleased to announce that the SITC Clinical Practice Guidelines (CPG) Mobile App has been selected by the American Association of Medical Society Executives (AAMSE) to receive the President’s Award as part of their Profiles of Excellence (PoE) Award Program. The PoE Awards are issued in five different categories to recognize organizations for their efforts in advancing the field of organized medicine ...
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The Society for Immunotherapy of Cancer (SITC) is pleased to announce the publication of a commentary detailing what is being described as a Crisis in Clinical Research . The clinical research pipeline is critical to ensuring continued development of novel treatments that can offer patients with cancer safe and effective options. Unfortunately, progress has slowed since the COVID-19 pandemic due to uncovered, systemic inefficiencies across critical ...
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In accordance with the Institute of Medicine’s Standards for Developing Trustworthy Clinical Practice Guidelines (CPGs), SITC CPGs undergo periodic evaluation to assess if new evidence necessitates modifications to recommendations, treatment algorithms, or other guideline content. This is done through our “ SITC Living Guidelines ” rapid update protocols designed to ensure SITC’s CPGs are up-to-date with cutting-edge thinking and incorporate the leading ...
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On behalf of the SITC Board of Directors, we are pleased to announce the publication of a new manuscript titled, “ Challenges and Opportunities in Cancer Immunotherapy: A Society for Immunotherapy of Cancer (SITC) Strategic Vision ” available now in the Journal for ImmunoTherapy of Cancer (JITC) . This manuscript is the first in a JITC Special Series — The Next Wave of Immuno-oncology: A Roadmap from the Society for Immunotherapy of Cancer ...
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In accordance with the Institute of Medicine’s Standards for Developing Trustworthy Clinical Practice Guidelines (CPGs), SITC CPGs undergo periodic evaluation to assess if new evidence necessitates modifications to recommendations, treatment algorithms, or other guideline content. This is done through our “ SITC Living Guidelines ” rapid update protocols designed to ensure SITC’s CPGs are up-to-date with cutting-edge thinking and incorporate the ...
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On behalf of the Society for Immunotherapy of Cancer (SITC) and in collaboration with the Association for Molecular Pathology (AMP) and the College of American Pathologists (CAP), we are pleased to announce the publication of a new manuscript titled " Recommendations for Tumor Mutational Burden Assay Validation and Reporting: A Joint Consensus Recommendation of the Association for Molecular Pathology, College of American Pathologists, and Society ...
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In accordance with the Institute of Medicine’s Standards for Developing Trustworthy Clinical Practice Guidelines (CPGs), SITC CPGs undergo periodic evaluation to assess if new evidence necessitates modifications to recommendations, treatment algorithms, or other guideline content. This is done through our “ SITC Living Guidelines ” rapid update protocols designed to ensure SITC’s CPGs are up-to-date with cutting-edge thinking and incorporate the leading ...
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On behalf of the Society for Immunotherapy of Cancer (SITC), the SITC Biomarkers Committee, the SITC Pathology Committee, and the 2024 SITC Clinical Immuno-Oncology Network ( SCION ) faculty, we are pleased to announce the publication of a commentary on measurement and interpretation of essential biomarkers in early clinical trials . Immunotherapy of cancer is now a mainstay of modern oncologic practice and is being integrated with conventional ...
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In accordance with the Institute of Medicine’s Standards for Developing Trustworthy Clinical Practice Guidelines (CPGs), SITC CPGs undergo periodic evaluation to assess if new evidence necessitates modifications to recommendations, treatment algorithms, or other guideline content. This is done through our “ SITC Living Guidelines ” rapid update protocols designed to ensure SITC’s CPGs are up-to-date with cutting-edge thinking and incorporate the leading ...
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On behalf of the society and the SITC Intratumoral Immunotherapy Clinical Trials Manuscript Development Group, we are pleased to announce the publication of a new manuscript “ Society for Immunotherapy of Cancer (SITC) recommendations on intratumoral immunotherapy clinical trials (IICT): from pre-malignant to metastatic disease ” in the Journal for ImmunoTherapy of Cancer . While intratumoral immunotherapies have the potential to boost anti-tumor ...
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Dr. Michael T. Lotze is Incoming Editor-in-Chief for the Journal for ImmunoTherapy of Cancer ( JITC ). As he transitions into his role with JITC , learn more about Dr. Lotze’s career, interest in JITC , and personal life. Career What inspired you to become a researcher? Dr. Lotze: My earliest experiences in research were a disaster; I worked on a project at Northwestern University over the summer after ...
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