Recombinant IL-2, IL-12, and IL-15 superagonist tagged with a naturally phosphorylated peptide motif (called alum-binding protein (ABP)) were robustly and consistently phosphorylated when purified from Fam20C kinase-expressing HEK293-F cells. ABP-tagged cytokines remained absorbed on alum for more than 2 weeks in vitro in the presence of mouse serum and largely retained functional bioactivity
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The Society for Immunotherapy of Cancer (SITC) hosted the 2021 SITC Cancer Immunotherapy Winter School, a comprehensive cancer immunotherapy education program, virtually on February 22-24, 2021. Available here are the presentation slides and video from Monday, February 22, 2021. Program...
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See matching library entry files - Meeting: 2021 SITC Cancer Immunotherapy Winter S...
Butterfield, PhD — University of Pittsburgh Research Article SAFETY, TUMOR TRAFFICKING AND IMMUNOGENICITY OF CHIMERIC ANTIGEN RECEPTOR (CAR)-T CELLS SPECIFIC FOR TAG-72 IN COLORECTAL CANCER Kristen M
The International Society for Biological Therapy of Cancer (iSBTc) 22 nd Annual Meeting November 2-4, 2007 Seaport World Trade Center in Boston, Massachusetts Program Organizers George Coukos, MD, PhD - University of Pennsylvania Medical Center F. Stephen Hodi, MD - Dana-Farber Cancer...
35 attachments
See matching library entry files - Experimental Design dLN Spleen AGN2a MIFKD AGN2a...
The International Society for Biological Therapy of Cancer (iSBTc) 22 nd Annual Meeting: Workshop November 1, 2007 Seaport World Trade Center in Boston, Massachusetts Program Organizers Bernard A. Fox, PhD - Earle A. Chiles Research Institute Thomas F. Gajewski, MD, PhD - University of...
15 attachments
See matching library entry files - Notch? Wnt?) Example 3A: IL-12 ...
The Society for Immunotherapy of Cancer (SITC) hosted the 2023 SITC Cancer Immunotherapy Winter School, a comprehensive cancer immunotherapy education program in Austin, Texas and live streamed on January 17-21, 2023 . Available here are the presentation slides and video from Friday,...
19 attachments
Complement downregulation promotes an inflammatory signature that renders colorectal cancer susceptible to immunotherapy Carsten Krieg, Lukas M Weber, Bruno Fosso, Marinella Marzano, Gary Hardiman, Monica M Olcina, Enric Domingo, Sahar El Aidy, Khalil Mallah, Mark D Robinson, Silvia Guglietta Journal for ImmunoTherapy of Cancer 2022;10:e004717 (22 September 2022) RESEARCH Summary: Microsatellite stable colorectal cancer (CRC) is immunologically cold and poorly responsive to checkpoint blockade, despite a well-established role for inflammation in driving tumorigenesis
COMPLEMENT DOWNREGULATION PROMOTES AN INFLAMMATORY SIGNATURE THAT RENDERS COLORECTAL CANCER SUSCEPTIBLE TO IMMUNOTHERAPY Carsten Krieg, Lukas M Weber, Bruno Fosso, Marinella Marzano, Gary Hardiman, Monica M Olcina, Enric Domingo, Sahar El Aidy, Khalil Mallah, Mark D Robinson, Silvia Guglietta Journal for ImmunoTherapy of Cancer 2022;10:e004717 (22 September 2022) RESEARCH Summary: Microsatellite stable colorectal cancer (CRC) is immunologically cold and poorly responsive to checkpoint blockade, despite a well-established role for inflammation in driving tumorigenesis
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