Dr. Ruella obtained his medical degree with high honors at the University of Torino, Italy, in 2007, and completed his specialization in clinical hematology in 2012. He worked as attending physician at the Hematology and Cell Therapy Division of the Mauriziano Hospital and was instructor at the Biotechnology School at the University of Torino. In 2012 he started his post-doctoral fellowship at the University of Pennsylvania in the Center for Cellular immunotherapies under the mentorship of Drs. Carl June and Saar Gill. Dr. Ruella is now Clinical Instructor and the Associate Director of Dr. June’s laboratory. His research is focused on the mechanisms of relapse after chimeric antigen receptor T cell (CART) immunotherapies with goal of rationally design innovative combined immunotherapies for relapsing/refractory leukemia and lymphoma. Dr. Ruella was awarded the inaugural SITC EMD-Serono Cancer Immunotherapy Clinical Fellowship (2014), the AACR-BMS Oncology Fellowship in Clinical Cancer Research (2015), the ASH Scholar Award (2016) and a NIH K99-R00 award (2017). He was also selected as ASH CRTI fellow in 2015 and ISCT/ASBMT CTTC scholar in 2015. Dr. Ruella is author of several peer-reviewed publications on targeted immunotherapies for hematological cancers and is inventor in five patents on CART therapy.