Immuno-Oncology Biomarkers: State of the Art

Starts:  May 16, 2018 8:00 AM (PT)
Ends:  May 17, 2018 5:00 PM (PT)

Workshop Overview Leadership Hotel and Travel Program Agenda

Program Purpose

The Immuno-Oncology Biomarkers Workshop will identify the next steps for action in immunotherapy biomarker development. It will provide a forum for energetic discussion about the collaborative efforts across several societies and consortia, make progress on identification and analysis of novel biomarkers, and tackle data analysis and specimen sharing. The final session will bring together representatives from the fields of immune-oncology research, infectious disease, autoimmune disease and cell biology to discuss opportunities for cross-disciplinary collaboration to advance biomarker development.

Panel discussions following each didactic presentation will allow all participants to contribute to the conversation, and to shape the innovative collaborations, next projects and other outputs that the SITC Immune Biomarkers Committee will incorporate over the next several years.

Intended Audience
The target audience for this program includes a broad representation from academia, biotech, pharma, government, researchers and early career individuals who wish to understand the biomarkers state of the art, discuss current hurdles to further success, and consider recommendations to move the field forward.

Educational Objectives
Upon completion of this meeting, participants will be able to:
- Discuss methods of validation of biomarkers to predict response to immunotherapy in cancer
- Describe effective approaches for data and specimen sharing related to biomarkers
- Describe how to collaborate across disciplines in order to advance biomarker research
- Describe existing processes and standards of practice regarding obtaining and processing biospecimens

Program Committee
Chair
– Lisa H. Butterfield, PhD – University of Pittsburgh
Mary L. Disis, MD, FACP – University of Washington
Bernard A. Fox, PhD – Earle A. Chiles Research InstituteRobert W. Franz Cancer Center
David Kaufman, MD, PhD – Bill & Melinda Gates Medical Center
Samir N. Khlief, MD – Georgetown University
Ena Wang, MD – AbbVie Biotherapeutics Corp.


Immuno-Oncology Biomarkers: State of the Art is supported in part by

AstraZeneca Pharmaceuticals LP, Bristol-Myers Squibb, Genentech, Incyte Corporation, and Merck & Co., Inc.


Hotel and Travel


Hotel

InterContinental Mark Hopkins Hotel
999 California Street, San Francisco, California 94108
Contact: 415-392-3434 | Fax: 415-421-3302

SITC has organized a block of rooms at $269 per night at the meeting hotel. Click here to book your hotel room on the InterContinental Mark Hopkins Hotel website. 
Click on the “BOOK NOW” link in the upper right hand corner of the page. Click "More Options" next to the gold Search button and the SITC discount Group Code “SIC” will automatically show and allow for the discounted group rates.   

To make your hotel reservation by phone, please contact the IHG Reservation Department at +1 800-662-4455. Identify yourself as a participant of the SITC Group (Code: SIC) in order to receive the negotiated rates of $269 per night.

Hotel Reservation deadline is Wednesday, May 2, 2018. After that time, reservations are considered based on availability.

Travel
Major Airports

The San Francisco Bay Area has three major airports with airline service.

For travel tips and security updates, please visit tsa.gov.

Shuttles
Intercontinental Mark Hopkins Hotel does not offer shuttle service. The BayPorter Express and SuperShuttle provide shuttle services from both San Francisco International Airport and Oakland International Airport to downtown San Francisco. 
Fares are approximate and subject to change.

Taxi Services
Taxi stands are located at all the major airports as well as most hotels, attractions and shopping centers. From the San Francisco International Airport to the InterContinental Mark Hopkins Hotel fares are approximately $45*. From the Oakland International Airport, the fare is $40* to the hotel. For more information about the taxi fares, please visit www.taxifarefinder.com.
*Fares are approximate and subject to change.

Trains
Trains arrive at the SFO International Terminal every 15 minutes and it's just 30 minutes to downtown San Francisco. A one-way ticket from SFO to downtown is approximately $9.65*. The BART (Bay Area Rapid Transit) station at SFO is located in the International Terminal. The Oakland Airport BART station is located just across from the Terminal 1 baggage claim area and a short walk from Terminal 2. *Fares are approximate and subject to change.

Registration
Online registration is closed.

Registration rates for members and non-members are listed below:


Member Type


Early Registration Rate


Onsite 
Registration Rate

Industry Member

$880

$930

Industry Non-Member

$1,100

$1,150

Non-Industry Member

$400

$450

Non-Industry Non-Member

$480

$530


Cancellation Policy

All cancellations must be received in writing. You may fax your cancellation to +1 888-289-9844 or e-mail education@sitcancer.org. Requests must be submitted by April 14, 2018. A $50 processing fee will be charged for all cancellations. All refunds will be processed after the programs; you will receive an e-mail confirmation. No refunds will be granted if cancellation is received after April 14, 2018. Special considerations will be given for health or family emergencies if requested in writing to education@sitcancer.org no later than 15 business days after the last day of the programs.


Program Agenda (Tentative Schedules as of April 9, 2018)

Wednesday May 16, 2018

Registration
Time:       7:00 – 8:00 a.m.
Location: Lobby Terrace

Breakfast
Time:       7:00 – 8:00 a.m.
Location: Lobby Terrace

Welcome and Introduction
Time:         8:00 – 8:15 a.m.
Location:   Peacock Court
Organizer: Lisa H. Butterfield, PhD – University of Pittsburgh

Session I: State of the Field
Time:          8:15 – 11:30 a.m.
Location:    Peacock Court
Co-Chairs: Stacey Adam, PhD – Foundation for the National Institutes of Health
                   Helen Chen, MD – National Cancer Institute

   
8:15 a.m. Overview of Cancer Immune Monitoring and Analysis Centers (CIMACs)-CIDC Network
                 William D. Merritt, PhD – National Cancer Institute
   
8:35 a.m. CIMAC Institutions and Cancer Immunologic Data Commons (CIDC)
                Sacha Gnjatic, PhD – Ichan School of Medicine at Mount Sinai
                Kara Davis, DO – Stanford University
                Ignacio Wistuba, MD – MD Anderson Cancer Center
                James Lindsay, PhD – Dana-Farber Cancer Institute

8:55 a.m. Comprehensive Biomarkers on Immunotherapy Clinical Trials: A Longitudinal Approach
                Ignacio Wistuba, MD – MD Anderson Cancer Center

9:00 a.m. The Partnership for Accelerating Cancer Therapies (PACT): A Public-Private Partnership to Aid Standardization of Immune Therapy Biomarkers
                Stacey Adam, PhD – Foundation for the National Institutes of Health 

9:20 a.m. Parker Institute for Cancer Immunotherapy's "TESLA" (Tumor NeoantigEN SeLection Alliance) Collaborative Project: Neoantigen Selection and the TESLA Consortium
                Fred Ramsdell, PhD – Parker Institute for Cancer Immunotherapy

9:40 a.m.      Break 
Location:       Lobby Terrace
  
9:55 a.m.  The MANAFEST Assay for Monitoring Anti-Tumor Immunity
                  
Kellie N. Smith, PhD – Johns Hopkins School of Medicine

10:15 a.m. Transcriptional Analysis of Peripheral Blood and Update on the ECOG1608 Trial
                  Davide Bedognetti, MD, PhD – Sidra Medical and Research Center

10:35 a.m. Panel Discussion 

11:30 a.m.     Lunch
Location:       Lobby Terrace


Session II: Validation of Biomarkers Identification and Analysis 
Time:         12:30 4:45 p.m.
Location:    Peacock Court
Co-Chairs: Bernard A. Fox, PhD – Earle A. Chiles Research Institute, Robert W. Franz Cancer Center
                  Sacha Gnjatic, PhD – Icahn School of Medicine at Mount Sinai

12:30 p.m. Introduction
                   Bernard A. Fox, PhD – Earle A. Chiles Research Institute, Robert W. Franz Cancer Center
   
12:35 p.m. Immunoscore Task Force
                   Bernard A. Fox, PhD – Earle A. Chiles Research Institute, Robert W. Franz Cancer Center

12:55 p.m. Multi-Parametric Biomarkers I: Seeing is Believing - Dissecting Local Immune-Tumor Interactions with Advanced Imaging Techniques
                   Chen Zhao, MD – National Institutes of Health

1:15 p.m. Multi-Parametric Biomarkers II: High-Dimensional Profiling of Cancer-Specific vs. Bystander Tumor Infiltrating T cells
                  Evan Newell, PhD – Singapore Immunology Network

1:35 p.m. Multispectral Imaging: Low Dimensionality Imaging Approach
                 Kurt Schalper, MD, PhD – Yale School of Medicine

1:55 p.m. Multispectral Imaging: Higher Dimensionality Imaging Approach
                 Michael Angelo, MD, PhD – Stanford University School of Medicine

2:15 p.m.        Break
Location:         Lobby Terrace

    
2:30 p.m. Machine Learning I
                  David Furman, PhD – Stanford University School of Medicine

2:50 p.m. Machine Learning II: Predicting Tumor Evolution from Immune Interactions
                  Marta Luksza, PhD – Institute for Advanced Study  

3:10 p.m. Panel Discussion
      
4:10 p.m. Closing Remarks
                  Bernard A. Fox, PhD – Earle A. Chiles Research Institute, Robert W. Franz Cancer Center

4:30 p.m. Reception


Thursday May 17, 2018

Registration
Time: 7:00 – 8:00 a.m.
Location: Lobby Terrace

Breakfast
Time: 7:00 – 8:00 a.m.
Location: Lobby Terrace

Session III: Data and Specimen Sharing
 
Time:          8:00 a.m. – 2:10 p.m.
Location:    Peacock Terrace
Co-Chairs: Samir N. Khleif, MD – Georgetown University
                   Elad Sharon, MD, MPH – National Cancer Institue
     
8:00 a.m. Introduction 
                Samir N. Khleif, MD – Georgetown University
     
8:05 a.m. Cancer Immunologic Data Commons (CIDC)
                 
James Lindsay, PhD – Dana-Farber Cancer Institute

8:25 a.m. Data Sharing for PACT and FNIH
                 
Stacey Adam, PhD – Foundation for the National Institutes of Health

8:45 a.m. Parker Institute for Cancer Immunotherapy
                 Pier Federico Gherardini, PhD – Parker Institute for Cancer Immunotherapy      

9:05 a.m. Stand Up To Cancer (SU2C)
                 Constantine Mitsiades, MD, PhD – Dana-Farber Cancer Institute

9:25 a.m. Industry Perspective: Bristol-Myers Squibb
                Shilpa Demes, PhD – Bristol-Myers Squibb   

9:40 a.m. Industry Perspective: Genentech
                Priti Hegde, PhD – Genentech

9:55 a.m. Academic Perspective
                Samir N. Khleif, MD – Georgetown University

10:15 a.m.       Break
Location:          Lobby Terrace
     
10:30 a.m. Cancer Immunotherapy Trials Network (CITN): Data Management and Specimen Sharing
                   Martin A. Cheever, MD – Fred Hutchinson Cancer Research Center
                   Steven P. Fling, PhD – Fred Hutchinson Cancer Research Center
  
10:50 a.m. American Association for Cancer Research (AACR) Project GENIE (Genomics Evidence Neoplasia Information Exchange): Driving Discovery in Immuno-oncology Through Data Sharing
                   Shawn Sweeney, PhD – American Association for Cancer Research
   
11:10 a.m. Oncology Research Information Exchange Network (ORIEN)
                   
Hongyue Dai, PhD – M2GEN

11:30 a.m.         Lunch
Location:            Lobby Terrace 
     
12:30 p.m. Immune-Related Adverse Events
                  John M. Kirkwood, MD – UPMC Hillman Cancer Center
      
12:50 p.m. Sparkathon Project TimIOs
                 Yana Najjar, MD – University of Pittsburgh                 
                 Randy Sweis, MD – University of Chicago
      
1:10 p.m. Panel Discussion 

2:10 p.m.           Break
Location:            Lobby Terrace


Session IV: Collaboration Across Disciplines
Time:         2:25 – 5:00 p.m.
Location:   Peacock Terrace
Co-Chairs: David Kaufman, MD, PhD – Bill & Melinda Gates Medical Research Institute
                  Francesco M. Marincola, MD
     
2:25 p.m. Introduction
                 David Kaufman, MD, PhD – Bill & Melinda Gates Medical Research Institute

      
2:30 p.m. Parker Institute for Cancer Immunotherapy
                 Theresa LaVallee, PhD – Parker Institute for Cancer Immunotherapy

     
2:50 p.m. Infectious Disease and Biomarkers I
                 David Kaufman, MD, PhD – Bill & Melinda Gates Medical Research Institute

3:10 p.m. Infectious Disease and Biomarkers II: Viral Biomarker Discovery using CyTOF
                 Holden T. Maecker, PhD – Stanford University Medical Center
     
3:30 p.m. Biomarkers in Authoimmunity
                 Zoe Quandt, MD – University of California, San Francisco

      
3:50 p.m. Panel Discussion 

      
4:50 p.m. Closing Remarks
                 Lisa H. Butterfield, PhD – University of Pittsburgh 

 

 

 

 


Location

InterContinental Mark Hopkins Hotel
999 California Street
San Francisco, CA 94108

Contact

SITC Education

Education@sitcancer.org