Oct. 11–12, 2021 • Online
Access the Program • Download Program Book • Enduring Materials • ePosters
Organizers
Susan M. Kaech, PhD –
Salk Institute
Anne O'Garra, PhD –
The Francis Crick InstituteAaron M. Ring, MD, PhD –
Yale University
Overview
This workshop will provide a deeper understanding of cytokines in immune cell proliferation, differentiation, and function, as they pertain to tumor immunobiology and cancer immunotherapy approaches. The virtual format assures a compelling program that can be held safely and successfully, and allows us to accommodate as many participants as possible.
The workshop will consist of scientific sessions and expert-led discussion on pressing topics in the field of cytokines in immunology and cancer immunotherapy. This workshop will encourage further investigation into the use of cytokines as solo therapeutic agents as well as in combination with cancer treatments by bringing together established experts and drawing talented new scientists and clinicians into the area of cytokines and immune cell differentiation and function.
Program Agenda
The program is hosted through Zoom Webinar.
Monday, Oct. 11, 2021
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Session I: History of Cytokine Immunotherapy
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Time:
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10–11:15 a.m. EDT |
10 a.m. EDT
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Introduction
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10:05 a.m. EDT
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History of Cytokine Immunotherapy – Basic Warren J. Leonard, MD – Laboratory of Molecular Immunology, NHLBI
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10:40 a.m. EDT
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History of Cytokine Immunotherapy – Clinical Kim A. Margolin, MD – St. John’s Cancer Institute
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Session II: Advances in IL-2/IL-15 Immunotherapy
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Time:
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11:15 a.m.–12:35 p.m. EDT
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11:15 a.m. EDT
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A Toolkit of Engineered Cytokines for Cancer Immunotherapy K. Christopher Garcia, PhD – Stanford University
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11:40 a.m. EDT
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IL-15 Mark Rubinstein, PhD – The Ohio State University Wexner Medical Center
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12:05 p.m. EDT
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Abstract Presentation
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12:20 p.m. EDT
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Abstract Presentation
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Break
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Time:
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12:35–12:50 p.m. EDT
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Session III: The Paradox of IL-10
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Time:
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12:50–2:10 p.m. EDT
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12:50 p.m. EDT
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Expectations and History of IL-10 Anne O' Garra, PhD, FRS, FMedSCI – The Francis Crick Institute
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1:15 p.m. EDT
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Clinical Data Martin Oft, MD – Synthekine
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1:40 p.m. EDT
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Abstract Presentation
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1:55 p.m. EDT
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Abstract Presentation
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Session IV: Inhibitor Cytokines
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Time:
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2:10–3:30 p.m. EDT
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2:10 p.m. EDT
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TGF-beta Zihai Li, MD, PhD – The Ohio State University
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2:35 p.m. EDT
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IL-35 Dario A.A. Vignali, PhD – University of Pittsburgh
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3:00 p.m. EDT |
Abstract Presentation
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3:15 p.m. EDT |
Abstract Presentation |
Session V: Interferons: Friend or Foe? |
Time:
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3:30–4:50 p.m. EDT
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3:30 p.m. EDT
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IFN-gamma Andy J. Minn, PhD – University of Pennsylvania
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3:55 p.m. EDT
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Type I Interferons John Teijaro, PhD – Scripps Research
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4:20 p.m. EDT |
Abstract Presentation
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4:35 p.m. EDT |
Abstract Presentation
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4:50 p.m. EDT
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Closing Remarks
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Tuesday, Oct. 12, 2021
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Session VI: Emerging Cytokines Therapies
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Time:
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10–11:25 a.m. EDT |
10 a.m. EDT
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Introduction
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10:05 a.m. EDT
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IL-18 Aaron M. Ring, MD, PhD – Yale School of Medicine
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10:30 a.m. EDT
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Intratumoral administration and retention of immune agonists to maximize therapeutic index K. Dane Wittrup, PhD – Koch Institute for Integrative Cancer Research at MIT
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10:55 a.m. EDT
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Abstract Presentation |
11:10 a.m. EDT
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Abstract Presentation
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Session VII: Cytokines in Cell Therapies
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Time:
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11:25 a.m. –12:15 p.m. EDT |
11:25 a.m. EDT
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Adoptive Th17 Therapies Chrystal M. Paulos, PhD – Winship Cancer Institute at Emory University
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11:50 a.m. EDT
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TRUCK Therapies Anthony Daniyan, MD –Memorial Sloan Kettering Cancer Center
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Minute-to-Win-It Presentation
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Time:
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12:05–12:40 p.m. EDT
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Break |
Time:
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12:40–12:55 p.m. EDT
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Session VIII: Cytokine Activity & Innate Immunity
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Time:
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12:55–1:55 p.m. EDT
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12:55 p.m. EDT
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NK Cells David H. Raulet, PhD – University of California, Berkeley
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1:20 p.m. EDT
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Boosting Innate Immunity to Overcome Immunotherapy Aquired Resistance Katerina Politi, PhD – Yale School of Medicine
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Session IX: Closing Keynote
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Time: |
1:45–2:45 p.m. |
1:45 p.m. EDT |
Keynote
Shannon J. Turley, PhD – Genentech, Inc.
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2:45 p.m. EDT |
Closing Remarks |