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On September 16, 2021, leading experts from the SITC Immune Checkpoint Inhibitor-related Adverse Events Guideline Expert Panel presented the "SITC Clinical Practice Guideline Webinar – Practical Management Pearls for Immune Checkpoint Inhibitor-related Adverse Events." This high-level webinar covered advanced concepts of toxicity management and risk factors drawing from recommendations within the Clinical Practice Guideline (CPG). The recorded webinar and presentation slides are available below.

Webinar Faculty:

• Co-moderator: Julie R. Brahmer, MD, MSc — Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (Expert Panel Chair)
• Co-moderator: Marc S. Ernstoff, MD — National Institutes of Health (Expert Panel Chair)
• David E. Gerber, MD — Harold C. Simmons Comprehensive Cancer Center, UT Southwestern (Expert Panel Member)
• Jarushka Naidoo, MBBCH, MHS — Beaumont RCSI Cancer Centre Dublin (Expert Panel Member)
• Jeffrey A. Sosman, MD — Northwestern University (Expert Panel Member)

The webinar discussed management of toxicities associated with immune checkpoint inhibitor (ICI) therapies and their risk factors, including:

• ICIs in high-risk populations
• introducing steroids and potential steroid-refractory irAEs
• identifying the irAE causative agent in combination therapies
• if and when to resume checkpoint inhibitor treatment after mitigating adverse events

Disclaimer: Due to the rapidly-evolving field of cancer immunotherapy, some of the content on this page may be out of date. For current information from SITC on cancer immunotherapy, please visit connected.sitcancer.org, or check out our free CPG mobile app.

This webinar is supported, in part, by independent medical education grant funding from Amgen and Merck & Co., Inc.
The SITC Clinical Practice Guidelines are produced by SITC and have no funding from outside sources.

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