Advances in our understanding of cancer immunology and the mechanisms by which cancer immunotherapies exert their effects have translated into increasingly positive patient outcomes.
The recent successes of immunotherapeutics, particularly immune checkpoint inhibitors, have served to demonstrate the power and potential of immune-based treatment strategies. Now there is a need to build upon what we have learned in order to effectively treat more patients with cancer.
Cancer Immunotherapy CONNECT, powered by SITC is your hub for live and online educational opportunities. This website provides access to all of the latest data in the field of tumor immunology and cancer immunotherapy. Connect to other researchers in our online Community and submit your manuscript to JITC to help drive progress.
This may be due to an alternate immune checkpoint, CD200 (OX2) checkpoint blockade. The immuneosuppressive CD200 protein shuts down the immune system through multiple mechanisms (Xiong ...
While I agree with Stephanie's detailed account, simply put checkpoint molecules are a signature of exhausted/ chronically stimulated lymphocytes and therefore serves as a feedback mechanism ...
Hi Stephanie many thanks for your ample reply. It makes sense indeed in order to secure self-antigens. However, is immune system evasion by means of immune checkpoint a matter of quality ...
The expression and regulation of immune checkpoints is an area of active investigation. In answer to your question regarding whether healthy tissues express immune checkpoint ...
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Launched in July of 2016, SITC presents the newest in a series of videos focusing on immunotherapy for NSCLC patients, the NSCLC Immunotherapy: Advancing HopeTM video provides an overview of the building blocks of the immune system and immunotherapy, while also highlighting some of the available FDA approved immunotherapy treatments and potential side effects, and the importance of clinical trials.
For more than 30 years SITC (Society for Immunotherapy of Cancer) has been fighting for treatment and a cure for cancer through research and collaboration. SITC members all over the world are leading the charge against cancer. We’re traveling the globe to meet these thought leaders and demonstrate the crucial work that they’re doing to impact advances in both the science and clinical application of immunotherapy.
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